Literature DB >> 26628308

Live kidney donation from a person with haemophilia.

Christopher McCauley1, Agnes Masengu2, Aisling E Courtney2, Gary Benson3.   

Abstract

There are many documented cases of a person with haemophilia successfully receiving a solid organ transplant, including liver and kidney. However, there is no literature reporting live organ donation by a person with haemophilia. Presumably, this is because the associated risks of excessive bleeding, inhibitor development after a period of intensive treatment with factor replacement and the possibility of variant Creutzfeldt-Jakob disease transmission in those previously treated with blood products, are considered excessive. This case describes a 24-year-old man who was diagnosed with mild haemophilia A during his pretransplant work up as a potential live kidney donor to his sister. He then went on to successfully donate his kidney, without complications. To the best of our knowledge, this is the first description of a person with haemophilia being a living organ donor. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26628308      PMCID: PMC4680236          DOI: 10.1136/bcr-2015-212735

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

1.  2509 living donor nephrectomies, morbidity and mortality, including the UK introduction of laparoscopic donor surgery.

Authors:  V G Hadjianastassiou; R J Johnson; C J Rudge; N Mamode
Journal:  Am J Transplant       Date:  2007-09-14       Impact factor: 8.086

2.  Successful haemodialysis and renal transplantation in a patient with haemophilia A.

Authors:  R A Koene; P G Gerlag; J L Jansen; A C Moulijn; S H Skotnicki; F J Debruyne; V A Kunst; P Geerdink; P G Wijdeveld
Journal:  Proc Eur Dial Transplant Assoc       Date:  1977

3.  A recurrent F8 mutation in Irish haemophilia A patients: evidence for a founder effect.

Authors:  P C Winter; H Egan; O McNulty; F G C Jones; J O'Donnell; P V Jenkins
Journal:  Haemophilia       Date:  2007-12-28       Impact factor: 4.287

4.  Outcome of orthotopic liver transplantation in patients with haemophilia.

Authors:  F H Gordon; P K Mistry; C A Sabin; C A Lee
Journal:  Gut       Date:  1998-05       Impact factor: 23.059

  4 in total

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