Jonathan L Eliason1, Dawn M Coleman2, Enrique Criado2, David B Kershaw3, Neal B Blatt3, David M Williams4, Narasimham L Dasika4, Kyung J Cho4, James C Stanley2. 1. Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, USA. jonaelia@med.umich.edu. 2. Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, USA. 3. Section of Pediatric Nephrology, Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA. 4. Division of Vascular/Interventional Radiology, Department of Radiology, University of Michigan, Ann Arbor, MI, USA.
Abstract
BACKGROUND: Percutaneous transluminal angioplasty (PTA) for the treatment of pediatric renovascular hypertension (RVH) in contemporary practice is accompanied with ill-defined complications. This study examines the mode of pediatric renal PTA failures and the results of their surgical management. METHODS: Twenty-four children underwent remedial operations at the University of Michigan from 1996 to 2014 for failures of renal PTA. Their clinical courses were retrospectively reviewed and results analyzed. RESULTS: Renal PTA of 32 arteries, including 13 with stenting, was performed for severe RVH in 12 boys and 12 girls, having a mean age of 9.3 years. Developmental ostial stenoses affected 22 children. PTA failures included: 27 restenoses and five thromboses. Remedial operations included: 13 renal artery-aortic reimplantations, one segmental renal artery-main renal artery reimplantation, ten aortorenal bypasses, one arterioplasty, one iliorenal bypass, and six nephrectomies for unreconstructable arteries; the latter all in children younger than 10 years. Follow-up averaged 2.1 years. Postoperatively, hypertension was cured, improved, or unchanged in 25, 54, and 21 %, respectively. There was no perioperative renal failure or mortality. CONCLUSIONS: Renal PTA for the treatment of pediatric RVH due to ostial disease may be complicated by failures requiring complex remedial operations or nephrectomy, the latter usually affecting younger children.
BACKGROUND: Percutaneous transluminal angioplasty (PTA) for the treatment of pediatric renovascular hypertension (RVH) in contemporary practice is accompanied with ill-defined complications. This study examines the mode of pediatric renal PTA failures and the results of their surgical management. METHODS: Twenty-four children underwent remedial operations at the University of Michigan from 1996 to 2014 for failures of renal PTA. Their clinical courses were retrospectively reviewed and results analyzed. RESULTS: Renal PTA of 32 arteries, including 13 with stenting, was performed for severe RVH in 12 boys and 12 girls, having a mean age of 9.3 years. Developmental ostial stenoses affected 22 children. PTA failures included: 27 restenoses and five thromboses. Remedial operations included: 13 renal artery-aortic reimplantations, one segmental renal artery-main renal artery reimplantation, ten aortorenal bypasses, one arterioplasty, one iliorenal bypass, and six nephrectomies for unreconstructable arteries; the latter all in children younger than 10 years. Follow-up averaged 2.1 years. Postoperatively, hypertension was cured, improved, or unchanged in 25, 54, and 21 %, respectively. There was no perioperative renal failure or mortality. CONCLUSIONS: Renal PTA for the treatment of pediatric RVH due to ostial disease may be complicated by failures requiring complex remedial operations or nephrectomy, the latter usually affecting younger children.
Authors: T Ino; M Kishiro; M Okubo; K Akimoto; K Nishimoto; K Yabuta; S Kawasaki; Y Hosoda Journal: Cardiovasc Intervent Radiol Date: 1998 Mar-Apr Impact factor: 2.740
Authors: Marike B Stadermann; Giovanni Montini; George Hamilton; Derek J Roebuck; Clare A McLaren; Michael J Dillon; Stephen D Marks; Kjell Tullus Journal: Nephrol Dial Transplant Date: 2009-10-21 Impact factor: 5.992
Authors: Dawn M Coleman; Jonathan L Eliason; Robert Beaulieu; Tatum Jackson; Monita Karmakar; David B Kershaw; Zubin J Modi; Santhi K Ganesh; Minhaj S Khaja; David Williams; James C Stanley Journal: J Vasc Surg Date: 2020-04-08 Impact factor: 4.268
Authors: Dawn M Coleman; Amer Heider; David Gordon; Santhi K Ganesh; Jonathan L Eliason; James C Stanley Journal: J Vasc Surg Date: 2020-04-08 Impact factor: 4.268