Literature DB >> 26628

Chromogenic substrate assay of plasma prekallikrein. With a note on its site of biosynthesis.

H Stormorken, A Baklund, M Gallimore, S Ritland.   

Abstract

A method for assaying plasma prekallikrein has been developed applying the chromogenic substrate Chromozym PK. Different variables have been investigated, and the final assay system was found to give a reproducible and reliable assay procedure. A normal value of 99.0 +/- 18% was found, the coefficient of variation being 7.9. Studies on material from patients with various liver diseases indicated that the main site of prekallikrein biosynthesis is the liver.

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Year:  1978        PMID: 26628     DOI: 10.1159/000214237

Source DB:  PubMed          Journal:  Haemostasis        ISSN: 0301-0147


  3 in total

1.  Complement, coagulation and fibrinolytic parameters in hereditary angioedema (HAE).

Authors:  W Cullmann; P M Kövary; N Müller; W Dick
Journal:  Clin Exp Immunol       Date:  1982-09       Impact factor: 4.330

2.  Hageman factor, high molecular weight kininogen, and prekallikrein in chronic liver disease.

Authors:  C Cordova; F Violi; C Alessandri; D Ferro; M Saliola; F Balsano
Journal:  J Clin Pathol       Date:  1986-09       Impact factor: 3.411

3.  Role of the plasma contact system in the pathogenesis of experimental anti-GBM glomerulonephritis.

Authors:  J Villaro; A Sánchez Ibarrola; A Purroy
Journal:  Clin Exp Immunol       Date:  1988-04       Impact factor: 4.330

  3 in total

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