Literature DB >> 26627306

Micro-fractional, directional skin tightening: A porcine model.

Elisabeth Russe1,2, Martin Purschke1, William A Farinelli1, Ying Wang1, Apostolos G Doukas1, Wikunda Limpiangkanan1, Fernanda H Sakamoto1, Joshua Tam1, Gottfried Wechselberger2, Richard Rox Anderson1.   

Abstract

BACKGROUND AND
OBJECTIVE: Skin changes are among the most visible signs of aging. Fractional ablative lasers improve skin quality by making small skin wounds that heal rapidly without scarring. While they improve skin texture and discoloration, there is minimal effect on skin laxity. This study was performed to assess skin shrinkage performed by removing multiple small full-thickness skin columns with coring needles combined with wound closure.
MATERIALS AND METHODS: In 5 swine 116 squares (3 cm(2) ) were demarcated for treatment and control sites. In treatment sites 10% of the skin was removed by full-thickness skin coring needles (19 gauge) and afterwards closed and compressed with an elastic adhesive dressing. This procedure was compared to puncturing the skin with standard hypodermic needles (without tissue removal) and subsequent closure with compressive dressing. Area and shape of sites were measured before and 28 days after treatment.
RESULTS: Test and control sites healed within a week without scarring. Coring with wound closure caused significant shrinkage after 28 days. The treated skin area was reduced by 9% (P < 0.0001) and the direction of shrinkage was influenced by the direction of wound closure. Coring without wound closure and puncturing the skin without tissue removal produced an insignificant 3% decrease in area.
CONCLUSION: Significant minimally invasive skin tightening in a preferred direction can be achieved by removing skin with coring needles followed by wound closure. The direction of shrinkage is influenced by the direction of micro-hole closure, irrespective of the skin tension lines. This approach may allow reshaping the skin in a desired direction without scarring.
© 2015 Wiley Periodicals, Inc.

Entities:  

Keywords:  coring needle; fractional ablative laser; photoaging; scarless facelift; skin aging; skin rejuvenation; wound closure

Mesh:

Year:  2015        PMID: 26627306     DOI: 10.1002/lsm.22444

Source DB:  PubMed          Journal:  Lasers Surg Med        ISSN: 0196-8092            Impact factor:   4.025


  3 in total

1.  Generation of DKK1 transgenic Tibet minipigs by somatic cell nuclear transfer (SCNT).

Authors:  Wei Liu; Li-Hong Wu; Min Yue; Bayaer Nashun; Hua Tang; Yan Chen; Bang-Zhu Chen; Jin Yuan; Dong Xiao; Wei-Wang Gu
Journal:  Oncotarget       Date:  2017-09-01

2.  Cytrellis: A Novel Microcoring Technology for Scarless Skin Removal: Summary of Three Prospective Clinical Trials.

Authors:  Jason N Pozner; Suzanne L Kilmer; Roy G Geronemus; Megan Jack; Jay A Burns; Michael S Kaminer
Journal:  Plast Reconstr Surg Glob Open       Date:  2021-10-29

Review 3.  New Medical Device and Therapeutic Approvals in Otolaryngology: State of the Art Review of 2021.

Authors:  Alexander M Choi; Michael J Brenner; Daniel Gorelik; Isaac D Erbele; Matthew G Crowson; Prajoy Kadkade; Masayoshi Takashima; Peter L Santa Maria; Robert S Hong; Austin S Rose; Benjamin T Ostrander; Cyrus C Rabbani; Robert J Morrison; Philip A Weissbrod; Alan D Tate; Joshua J Kain; Ioan A Lina; Scott R Shaffer; Omar G Ahmed
Journal:  OTO Open       Date:  2022-09-23
  3 in total

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