Literature DB >> 26625839

Chemical modification of arglabin and biological activity of its new derivatives.

S M Adekenov1.   

Abstract

This review summarizes the results of own research on chemical modification of the molecule of sesquiterpene lactone arglabin from Artemisia glabella Kar. et Kir. Over 70 new arglabin derivatives were obtained which are polyfunctional compounds with oxy functions, atoms of haloids, phosphorus, nitrogen, and cyclopropane fragments. For the first time the results of bioscreening of new arglabin derivatives are reported.
Copyright © 2015. Published by Elsevier B.V.

Entities:  

Keywords:  Anti-inflammatory; Antifungal; Antimicrobial activities; Antitumoral; Artemisia glabella Kar. et Kir.; Immunomodulatory action; Phagocytosis stimulating; Sesquiterpene lactone arglabin; Structure–activity

Mesh：

Substances：

Year:  2015        PMID： 26625839     DOI： 10.1016/j.fitote.2015.11.018

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  5 in total

1.  The natural sesquiterpene lactones arglabin, grosheimin, agracin, parthenolide, and estafiatin inhibit T cell receptor (TCR) activation.

Authors:  Igor A Schepetkin; Liliya N Kirpotina; Pete T Mitchell; Аnarkul S Kishkentaeva; Zhanar R Shaimerdenova; Gayane A Atazhanova; Sergazy M Adekenov; Mark T Quinn
Journal:  Phytochemistry       Date:  2017-12-22       Impact factor: 4.072

Review 2.  Phytochemistry and pharmacological activity of the genus artemisia.

Authors:  Dheeraj Bisht; Deepak Kumar; Dharmendra Kumar; Kamal Dua; Dinesh Kumar Chellappan
Journal:  Arch Pharm Res       Date:  2021-04-24       Impact factor: 6.010

Review 3.  Traditional Use, Phytochemical Profiles and Pharmacological Properties of Artemisia Genus from Central Asia.

Authors:  Aliya Nurlybekova; Aidana Kudaibergen; Aizhan Kazymbetova; Magzhan Amangeldi; Aizhamal Baiseitova; Meirambek Ospanov; Haji Akber Aisa; Yang Ye; Mohamed Ali Ibrahim; Janar Jenis
Journal:  Molecules       Date:  2022-08-11       Impact factor: 4.927

Review 4.  Sesquiterpene Lactones: Promising Natural Compounds to Fight Inflammation.

Authors:  Melanie S Matos; José D Anastácio; Cláudia Nunes Dos Santos
Journal:  Pharmaceutics       Date:  2021-06-30       Impact factor: 6.321

5.  Syntheses Based on 3,4α-Epoxy-1,5,7α,6β(H)-guai-10(14),11(13)-dien-6,12-olide.

Authors:  Sergazy Adekenov
Journal:  Molecules       Date:  2022-03-13       Impact factor: 4.411
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.