Literature DB >> 26623069

Short-term outcomes between laparoscopy-assisted and open colorectomy for colorectal cancer in elderly patients: A case-matched control study.

Zexian Chen1, Xiaosheng He1, Juanni Huang2, Yike Zeng3, Lei Lian1, Xiaojian Wu1, Jian Lei3, Jianping Wang1, Ping Lan1.   

Abstract

With the increase in life expectancy, surgical intervention for colorectal cancer (CRC) is more frequently performed in elderly patients. This retrospective study was designed to compare short-term outcomes between laparoscopy-assisted colorectomy (LC) and open colorectomy (OC) in elderly patients with CRC. A total of 89 CRC patients aged ≥75 years undergoing LC were matched with 89 counterparts undergoing OC. The matching criteria included general information and preoperative status. The operative data and short-term postoperative outcomes were compared. Following analysis, patients in the LC and OC groups were comparable for the matching criteria. Compared with the OC group, the operative time was longer (P=0.046), but the estimated blood loss (P<0.001) and intraoperative transfusion (P=0.042) were less in the LC group. As regards short-term postoperative outcomes, the duration of postoperative hospital stay was shorter (P=0.001) and the incidence of wound complications was lower (P=0.044) with LC. The overall complication, other complications, reoperation and mortality rates were comparable between the two groups. In conclusion, considering the operative variables and short-term outcomes, LC is a safe procedure and appears to be superior to OC for elderly patients with CRC.

Entities:  

Keywords:  colorectal cancer; elderly patients; laparoscopy-assisted colorectomy; open colorectomy; short-term complications

Year:  2015        PMID: 26623069      PMCID: PMC4534871          DOI: 10.3892/mco.2015.585

Source DB:  PubMed          Journal:  Mol Clin Oncol        ISSN: 2049-9450


  22 in total

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3.  Clinical advantages of laparoscopic colorectal cancer surgery in the elderly.

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6.  Changed trends of cancer mortality in the elderly.

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7.  Outcomes of laparoscopic colorectal surgery: data from the Nationwide Inpatient Sample 2009.

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Review 9.  Laparoscopic versus open surgery for colon cancer: a meta-analysis of 5-year follow-up outcomes.

Authors:  Baoshan Di; Yan Li; Kongping Wei; Xiaojuan Xiao; Jie Shi; Yan Zhang; Xiaoqin Yang; Peng Gao; Ke Zhang; Yuan Yuan; Dongzhi Zhang; Xiaodong Wei; Shaoguang Liu; Jianping Wang; Xuebing Wang; Yingmei Zhang; Hui Cai
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10.  Outcomes of elective laparoscopic colorectal operations in octogenarians at a district general hospital in South East England.

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  1 in total

1.  Cost-effectiveness Evaluation of Targeted Surgical and Endoscopic Therapies for Early Colorectal Adenocarcinoma Based on Biomarker Profiles.

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Journal:  JAMA Netw Open       Date:  2020-03-02
  1 in total

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