Literature DB >> 26622651

MRI and MR spectroscopy findings of the evolution of an intracranial germinoma: A case report.

Jun Li1, Xue-Yan Zhang2, Bin Wang2, Jun-Zu Geng1.   

Abstract

Intracranial germinomas (IG) are rare tumors that typically occur in the pineal gland and suprasellar region of the brain. IG can be successfully treated with radiation therapy and its recurrence is rare. The present study reports the case of a patient with IG involving the pineal and suprasellar regions. The patient was treated with radiotherapy, achieving significant remission. However, recurrence was discovered 10 months later. The patient was subsequently treated with chemotherapy and radiotherapy, resulting in gradual remission. The patient had recovered 2 months later and was in good health. The entire evolution process, including magnetic resonance (MR) imaging and MR spectroscopy findings, are described herein. The present case suggests that MR spectroscopy may be useful for monitoring the effects of treatment.

Entities:  

Keywords:  evolution; intracranial germinoma; magnetic resonance imaging; magnetic resonance spectroscopy

Year:  2015        PMID: 26622651      PMCID: PMC4509071          DOI: 10.3892/ol.2015.3351

Source DB:  PubMed          Journal:  Oncol Lett        ISSN: 1792-1074            Impact factor:   2.967


  10 in total

1.  MRI of intracranial germ-cell tumours.

Authors:  L Liang; Y Korogi; T Sugahara; I Ikushima; Y Shigematsu; T Okuda; M Takahashi; M Kochi; Y Ushio
Journal:  Neuroradiology       Date:  2002-01-05       Impact factor: 2.804

2.  Pure pineal germinomas: analysis of gender incidence.

Authors:  V Cuccia; M Galarza
Journal:  Acta Neurochir (Wien)       Date:  2006-06-23       Impact factor: 2.216

3.  Long-term follow-up and quality of life in patients with intracranial germinoma.

Authors:  T Martens; R Rotermund; C Zu Eulenburg; M Westphal; J Flitsch
Journal:  Neurosurg Rev       Date:  2014-04-09       Impact factor: 3.042

4.  Late recurrence of pineal germinoma.

Authors:  Markus Wenger; Karl O Lövblad; Regula Markwalder; Ethan Taub
Journal:  Surg Neurol       Date:  2002-01

5.  Pattern of relapse and outcome of non-metastatic germinoma patients treated with chemotherapy and limited field radiation: the SFOP experience.

Authors:  Claire Alapetite; Herve Brisse; Catherine Patte; Marie Anne Raquin; Genevieve Gaboriaud; Christian Carrie; Jean Louis Habrand; Philippe Thiesse; Jean Claude Cuilliere; Valerie Bernier; M Ben-Hassel; Didier Frappaz; Marie Christine Baranzelli; Eric Bouffet
Journal:  Neuro Oncol       Date:  2010-08-17       Impact factor: 12.300

6.  Proton MR spectroscopy and diffusion-weighted MR imaging for the diagnosis of intracranial tuberculomas. Report of two cases.

Authors:  Makio Kaminogo; Hideki Ishimaru; Minoru Morikawa; Yaeko Suzuki; Shobu Shibata
Journal:  Neurol Res       Date:  2002-09       Impact factor: 2.448

7.  Intracranial germ cell tumors: a comprehensive update of the European data.

Authors:  G Calaminus; M Bamberg; M C Baranzelli; Y Benoit; L C di Montezemolo; F Fossati-Bellani; H Jürgens; H J Kühl; H G Lenard; M L Curto
Journal:  Neuropediatrics       Date:  1994-02       Impact factor: 1.947

8.  TEMPORARY REMOVAL: MRI and 1H-MRS on diagnosis of pineal region tumors.

Authors:  Tong Tong; Yao Zhenwei; Feng Xiaoyuan
Journal:  Clin Imaging       Date:  2012-06-08       Impact factor: 1.605

9.  Early response to chemotherapy as an indicator for the management of germinoma-like tumors of the pineal and/or suprasellar regions.

Authors:  Ryuta Saito; Toshihiro Kumabe; Masayuki Kanamori; Yukihiko Sonoda; Mika Watanabe; Shunji Mugikura; Shoki Takahashi; Teiji Tominaga
Journal:  J Clin Neurosci       Date:  2013-11-12       Impact factor: 1.961

Review 10.  Late recurrence of a pineal germinoma 14 years after radiation and chemotherapy: a case report and review of the literature.

Authors:  Snjezana Janjetovic; Carsten Bokemeyer; Walter Fiedler; Thorsten Frenzel; Gabriele Calaminus; Friedemann Honecker
Journal:  Onkologie       Date:  2013-05-21
  10 in total

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