| Literature DB >> 26621866 |
António José Cruz1, Alexandra Castro1.
Abstract
Systemic lupus erythaematosus (SLE) is known to involve the reticuloendothelial system, but spontaneous splenic rupture (SSR) in the context of the disease is a very rare complication. We observed a 61-year-old woman with an unremarkable previous medical history who presented with SSR and underwent an emergency splenectomy. The histopathological analysis of the specimen revealed signs of vasculitis. On review of symptoms with the patient, a history of oligoarthralgia, photosensitivity, xerostomia and Raynaud phenomenon was elicited. Laboratory investigations revealed lymphopaenia, mild proteinuria and positive antinuclear and anti-dsDNA antibodies. The patient was started on hydroxychloroquine and the disease has since remained silent. This article addresses the rare association between SLE and SSR. 2015 BMJ Publishing Group Ltd.Entities:
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Year: 2015 PMID: 26621866 PMCID: PMC4680268 DOI: 10.1136/bcr-2015-212531
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X