Gustavo G Nascimento1,2, Fábio R M Leite3,4, Marcos B Correa3, Marco A Peres4, Flávio F Demarco3,5. 1. Post-Graduate Program in Dentistry, Federal University of Pelotas, 457, Gonçalves Chaves St, 5th floor, Pelotas, RS, 96015-560, Brazil. gustavo.gnascimento@hotmail.com. 2. Australian Research Centre for Population Oral Health (ARCPOH), School of Dentistry, The University of Adelaide, Adelaide, SA, 5005, Australia. gustavo.gnascimento@hotmail.com. 3. Post-Graduate Program in Dentistry, Federal University of Pelotas, 457, Gonçalves Chaves St, 5th floor, Pelotas, RS, 96015-560, Brazil. 4. Australian Research Centre for Population Oral Health (ARCPOH), School of Dentistry, The University of Adelaide, Adelaide, SA, 5005, Australia. 5. Post-Graduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.
Abstract
AIM: The aim of this study was to systematically review the literature to answer the questions: (i) "Is periodontal treatment effective to improve clinical and immunological conditions in obese subjects?"; (ii) "Do obese subjects present different clinical and immunological response after periodontal therapy when compared to non-obese subjects?" METHODS: Searches were performed in six databases up to August 2014. Interventional studies were included if the following data were described: (1) Obesity/overweight assessment; (2) definition of periodontal disease; (3) periodontal therapy; (4) inflammatory marker in serum/plasma, and/or clinical parameters of periodontal disease. Assessment of quality was performed with the Downs and Black scale. Meta-analyses were conducted with the available data. RESULTS: Of 489 articles, 5 were included, and only 3 proceeded to meta-analysis of clinical outcomes. Included studies presented fair methodological quality. Statistical analysis demonstrated that periodontal therapy in obese subjects was effective to improve clinical outcomes. No clinical differences between post-therapy results of obese and non-obese were observed. Effects of periodontal therapy on inflammatory markers remain unclear. CONCLUSIONS: Periodontal treatment seems to be effective to improve healing in obese individuals. No differences on periodontal healing between obese and non-obese subjects were observed; however, only limited and fragile base of evidence was available for analysis. CLINICAL RELEVANCE: Periodontal treatment is effective to improve clinical and immunological periodontal parameters in adults. Also, obesity seems to not modify the periodontal healing after treatment.
AIM: The aim of this study was to systematically review the literature to answer the questions: (i) "Is periodontal treatment effective to improve clinical and immunological conditions in obese subjects?"; (ii) "Do obese subjects present different clinical and immunological response after periodontal therapy when compared to non-obese subjects?" METHODS: Searches were performed in six databases up to August 2014. Interventional studies were included if the following data were described: (1) Obesity/overweight assessment; (2) definition of periodontal disease; (3) periodontal therapy; (4) inflammatory marker in serum/plasma, and/or clinical parameters of periodontal disease. Assessment of quality was performed with the Downs and Black scale. Meta-analyses were conducted with the available data. RESULTS: Of 489 articles, 5 were included, and only 3 proceeded to meta-analysis of clinical outcomes. Included studies presented fair methodological quality. Statistical analysis demonstrated that periodontal therapy in obese subjects was effective to improve clinical outcomes. No clinical differences between post-therapy results of obese and non-obese were observed. Effects of periodontal therapy on inflammatory markers remain unclear. CONCLUSIONS: Periodontal treatment seems to be effective to improve healing in obese individuals. No differences on periodontal healing between obese and non-obese subjects were observed; however, only limited and fragile base of evidence was available for analysis. CLINICAL RELEVANCE: Periodontal treatment is effective to improve clinical and immunological periodontal parameters in adults. Also, obesity seems to not modify the periodontal healing after treatment.
Authors: Birte Holtfreter; Jasim M Albandar; Thomas Dietrich; Bruce A Dye; Kenneth A Eaton; Paul I Eke; Panos N Papapanou; Thomas Kocher Journal: J Clin Periodontol Date: 2015-05-07 Impact factor: 8.728
Authors: Anna Damanaki; Svenja Memmert; Marjan Nokhbehsaim; Ali Abedi; Birgit Rath-Deschner; Andressa Nogueira; James Deschner Journal: Int J Mol Sci Date: 2021-12-11 Impact factor: 5.923