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Literature DB >> 26620403

The phenotypic screening pendulum swings.

Asher Mullard.

Abstract

Mesh：

Year: 2015 PMID： 26620403 DOI： 10.1038/nrd4783

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

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1 in total

1. Stem-cell discovery platforms yield first clinical candidates.

Authors: Asher Mullard
Journal: Nat Rev Drug Discov Date: 2015-09 Impact factor: 84.694

1 in total

13 in total

Review 1. Opportunities and challenges in phenotypic drug discovery: an industry perspective.

Authors: John G Moffat; Fabien Vincent; Jonathan A Lee; Jörg Eder; Marco Prunotto
Journal: Nat Rev Drug Discov Date: 2017-07-07 Impact factor: 84.694

Review 2. Emerging Targets for Cardiovascular Disease Prevention in Diabetes.

Authors: Nathan O Stitziel; Jenny E Kanter; Karin E Bornfeldt
Journal: Trends Mol Med Date: 2020-05-15 Impact factor: 11.951

3. Improved Scalability of Neuron-Based Phenotypic Screening Assays for Therapeutic Discovery in Neuropsychiatric Disorders.

Authors: Timothy P Spicer; Christopher Hubbs; Thomas Vaissiere; Deanna Collia; Camilo Rojas; Murat Kilinc; Kyle Vick; Franck Madoux; Pierre Baillargeon; Justin Shumate; Kirill A Martemyanov; Damon T Page; Sathya Puthanveettil; Peter Hodder; Ronald Davis; Courtney A Miller; Louis Scampavia; Gavin Rumbaugh
Journal: Mol Neuropsychiatry Date: 2017-11-17

Review 4. Engineered Liver Platforms for Different Phases of Drug Development.

Authors: Brenton R Ware; Salman R Khetani
Journal: Trends Biotechnol Date: 2016-09-02 Impact factor: 19.536

Review 5. Leveraging human genetics to guide drug target discovery.

Authors: Nathan O Stitziel; Sekar Kathiresan
Journal: Trends Cardiovasc Med Date: 2016-08-26 Impact factor: 6.677

Review 6. Principle and design of pseudo-natural products.

Authors: George Karageorgis; Daniel J Foley; Luca Laraia; Herbert Waldmann
Journal: Nat Chem Date: 2020-02-03 Impact factor: 24.427

Review 7. Inverse Drug Discovery identifies weak electrophiles affording protein conjugates.

Authors: Gabriel M Kline; Karina Nugroho; Jeffery W Kelly
Journal: Curr Opin Chem Biol Date: 2022-01-20 Impact factor: 8.822

Review 8. Zebrafish small molecule screens: Taking the phenotypic plunge.

Authors: Charles H Williams; Charles C Hong
Journal: Comput Struct Biotechnol J Date: 2016-09-18 Impact factor: 7.271

9. Discovery of Novel Small Molecule Inhibitors of VEGF Expression in Tumor Cells Using a Cell-Based High Throughput Screening Platform.

Authors: Liangxian Cao; Marla Weetall; Jenelle Bombard; Hongyan Qi; Tamil Arasu; William Lennox; Jean Hedrick; Josephine Sheedy; Nicole Risher; Peter C Brooks; Panayiota Trifillis; Christopher Trotta; Young-Choon Moon; John Babiak; Neil G Almstead; Joseph M Colacino; Thomas W Davis; Stuart W Peltz
Journal: PLoS One Date: 2016-12-16 Impact factor: 3.240

10. Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins.

Authors: Roland Hellinger; Kathrin Thell; Mina Vasileva; Taj Muhammad; Sunithi Gunasekera; Daniel Kümmel; Ulf Göransson; Christian W Becker; Christian W Gruber
Journal: Front Chem Date: 2017-10-11 Impact factor: 5.221