Literature DB >> 26619480

Vancomycin Dosing Practices, Trough Concentrations, and Predicted Area Under the Curve in Children With Suspected Invasive Staphylococcal Infections.

Rebecca F Chhim1, Sandra R Arnold2, Kelley R Lee3.   

Abstract

Recent guidelines recommend empiric vancomycin dosing of 60 mg/kg per day and consideration of higher trough concentrations (15-20 mcg/mL) in children with invasive infections. In this study, we report a retrospective review evaluating the dose/trough relationship and predicted area under the curve in pediatric patients receiving vancomycin for invasive staphylococcal infections.
© The Author 2012. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Area Under the Curve; Children; Methicillin-Resistant Staphylococcus aureus; Trough Concentration; Vancomycin

Year:  2012        PMID： 26619480     DOI： 10.1093/jpids/pis083

Source DB:  PubMed          Journal:  J Pediatric Infect Dis Soc        ISSN： 2048-7193            Impact factor:   3.164


  15 in total

1.  Balancing vancomycin efficacy and nephrotoxicity: should we be aiming for trough or AUC/MIC?

Authors:  Karisma Patel; Ashley S Crumby; Holly D Maples
Journal:  Paediatr Drugs       Date:  2015-04       Impact factor: 3.022

Review 2.  Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in Children: a Reappraisal of Vancomycin.

Authors:  Roopali Sharma; Margaret R Hammerschlag
Journal:  Curr Infect Dis Rep       Date:  2019-09-05       Impact factor: 3.725

Review 3.  Dose optimisation of antibiotics in children: application of pharmacokinetics/pharmacodynamics in paediatrics.

Authors:  Kevin J Downes; Andrea Hahn; Jason Wiles; Joshua D Courter; Alexander A Vinks
Journal:  Int J Antimicrob Agents       Date:  2013-12-17       Impact factor: 5.283

4.  Evaluation of Target Attainment of Vancomycin Area Under the Curve in Children With Methicillin-Resistant Staphylococcus Aureus Bacteremia.

Authors:  Andrea Hahn; Robert W Frenck; Mary Allen-Staat; Yuanshu Zou; Alexander A Vinks
Journal:  Ther Drug Monit       Date:  2015-10       Impact factor: 3.681

5.  Validation of a pediatric population pharmacokinetic model for vancomycin.

Authors:  Andrea Hahn; Robert W Frenck; Yuanshu Zou; Alexander A Vinks
Journal:  Ther Drug Monit       Date:  2015-06       Impact factor: 3.681

6.  Early Bayesian Dose Adjustment of Vancomycin Continuous Infusion in Children: a Randomized Controlled Trial.

Authors:  Romain Berthaud; Sihem Benaboud; Déborah Hirt; Mathieu Genuini; Mehdi Oualha; Martin Castelle; Coralie Briand; Solène Artru; Lorenzo Norsa; Olivia Boyer; Frantz Foissac; Naïm Bouazza; Jean-Marc Tréluyer
Journal:  Antimicrob Agents Chemother       Date:  2019-10-07       Impact factor: 5.191

7.  Epidemiology of Methicillin-Resistant Staphylococcus aureus Bacteremia in Children.

Authors:  Rana F Hamdy; Alice J Hsu; Chris Stockmann; Jared A Olson; Matthew Bryan; Adam L Hersh; Pranita D Tamma; Jeffrey S Gerber
Journal:  Pediatrics       Date:  2017-05-05       Impact factor: 7.124

8.  Healthcare-associated Staphylococcus aureus Bacteremia in Children: Evidence for Reverse Vancomycin Creep and Impact of Vancomycin Trough Values on Outcome.

Authors:  J Chase McNeil; Eric Y Kok; Andrea R Forbes; Linda Lamberth; Kristina G Hulten; Jesus G Vallejo; Edward O Mason; Sheldon L Kaplan
Journal:  Pediatr Infect Dis J       Date:  2016-03       Impact factor: 2.129

Review 9.  The Relationship Between Vancomycin Trough Concentrations and AUC/MIC Ratios in Pediatric Patients: A Qualitative Systematic Review.

Authors:  Stacey Tkachuk; Kyle Collins; Mary H H Ensom
Journal:  Paediatr Drugs       Date:  2018-04       Impact factor: 3.022

10.  Assessment of Empiric Vancomycin Regimen in the Neonatal Intensive Care Unit.

Authors:  Ruthdol Ywaya; Brandi Newby
Journal:  Can J Hosp Pharm       Date:  2018-06-30
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