| Literature DB >> 26619378 |
Bin Zheng1, Lin Su2, Huizhuo Pan1, Beibei Hou2, Ying Zhang1, Fang Zhou2, Xiaoli Wu1, Xiaoqun Gong1, Hanjie Wang1, Jin Chang1.
Abstract
An NIR-controlled gene expression system based on upconverting rods (UCRs) is demonstrated. The UCRs can harvest the "biocompatible" NIR light and convert it into local UV light, resulting in cleavage of the photosensitive molecule (4-(hydroxymethyl)-3-nitrobenzoic acid, ONA) and on-demand release of gene carriers, thus realizing target gene expression at high spatial and temporal resolutions.Entities:
Keywords: NIR-remote selected activation; gene expression; light-sensitive molecules; photosensitivity; upconverting rods
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Year: 2015 PMID： 26619378 DOI： 10.1002/adma.201503961
Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849