| Literature DB >> 26618995 |
Vivian Iida Avelino-Silva1,2, Marcos da Silva Freire3, Vanderson Rocha2, Celso Arrais Rodrigues2, Yana Sarkis Novis2, Ester C Sabino1,4, Esper Georges Kallas1,2,5.
Abstract
We report the case of a cord blood haematopoietic stem cell transplant recipient who was vaccinated for Yellow Fever (YF) 7 days before initiating chemotherapy and had persistent YF antibodies more than 3 years after vaccination. Since the stem cell donor was never exposed to wild YF or to the YF vaccine, and our patient was not exposed to YF or revaccinated, this finding strongly suggests the persistence of recipient immunity. We briefly discuss potential consequences of incomplete elimination of recipient's leukocytes following existing haematopoietic cancer treatments.Entities:
Keywords: cord blood stem cell transplant; immunosuppression; vaccine; yellow fever
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Year: 2015 PMID: 26618995 PMCID: PMC4962932 DOI: 10.1080/21645515.2015.1112475
Source DB: PubMed Journal: Hum Vaccin Immunother ISSN: 2164-5515 Impact factor: 3.452