| Literature DB >> 266175 |
Abstract
The interpretation of animal survival experiments in which disease incidence is determined at death or following sacrifice is shown to involve certain ambiguities. In particular, quantities of interest such as the expected duration of life for an animal contracting a specific disease at a specific age are found to be nonidentifiable. An example is constructed in which two populations of animals will appear similar to the experimenter but in which animals contracting a particular disease in one population may have double the life expectancy of similarly afflicted animals in the other population.Entities:
Mesh:
Year: 1977 PMID: 266175 PMCID: PMC430749 DOI: 10.1073/pnas.74.4.1338
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205