Literature DB >> 26614560

Chitosan as a starting material for wound healing applications.

V Patrulea1, V Ostafe2, G Borchard3, O Jordan4.   

Abstract

Chitosan and its derivatives have attracted great attention due to their properties beneficial for application to wound healing. The main focus of the present review is to summarize studies involving chitosan and its derivatives, especially N,N,N-trimethyl-chitosan (TMC), N,O-carboxymethyl-chitosan (CMC) and O-carboxymethyl-N,N,N-trimethyl-chitosan (CMTMC), used to accelerate wound healing. Moreover, formulation strategies for chitosan and its derivatives, as well as their in vitro, in vivo and clinical applications in wound healing are described.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Biopolymers; Carboxymethyl chitosan; Chitosan; Chitosan (PubChem CID: 21896651); Chitosan derivatives; Drug delivery; Polyelectrolytes; Skin regeneration; Trimethyl chitosan; Wound dressings; Wound healing

Mesh：

Substances：

Year:  2015        PMID： 26614560     DOI： 10.1016/j.ejpb.2015.08.004

Source DB:  PubMed          Journal:  Eur J Pharm Biopharm        ISSN： 0939-6411            Impact factor:   5.571


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