| Literature DB >> 26614376 |
Dik J Kwekkeboom1, Eric P Krenning2.
Abstract
Peptide receptor radionuclide therapy (PRRT) is a promising new treatment modality for inoperable or metastasized gastroenteropancreatic neuroendocrine tumors patients. Most studies report objective response rates in 15% to 35% of patients. Progression-free (PFS) and overall survival (OS) compare favorably with that for somatostatin analogues, chemotherapy, or newer, "targeted" therapies. Prospective, randomized data regarding the potential PFS and OS benefit of PRRT compared with standard therapies is anticipated.Entities:
Keywords: Carcinoid; Neuroendocrine tumor; PRRT; Radionuclide therapy; Treatment
Mesh:
Substances:
Year: 2016 PMID: 26614376 DOI: 10.1016/j.hoc.2015.09.009
Source DB: PubMed Journal: Hematol Oncol Clin North Am ISSN: 0889-8588 Impact factor: 3.722