Literature DB >> 26614029

Emerging Bladder Cancer Biomarkers and Targets of Therapy.

George J Netto1, Laura J Tafe2.   

Abstract

Bladder cancer is a heterogeneous disease characterized by complex networks of molecular alterations and gene expression. This review summarizes some of the recent genomic studies that have further advanced the understanding of the pathways driving bladder cancer, highlighting several important biomarkers and potential targeted therapeutic strategies that are now in clinical trials. In addition, noninvasive techniques to evaluate biomarkers in patients' urine and serum for early detection and surveillance are discussed.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Biomarkers; Bladder cancer; Clinical trials; Genomics; Targeted therapy; Urothelial carcinoma

Mesh：

Substances：

Year:  2016        PMID： 26614029     DOI： 10.1016/j.ucl.2015.08.006

Source DB:  PubMed          Journal:  Urol Clin North Am        ISSN： 0094-0143            Impact factor:   2.241


  7 in total

Review 1.  Toward personalized management in bladder cancer: the promise of novel molecular taxonomy.

Authors:  Marie-Lisa Eich; Lars Dyrskjøt; George J Netto
Journal:  Virchows Arch       Date:  2017-04-21       Impact factor: 4.064

2.  Multiorientation Simultaneous Computation of Back-Projection CT Image Reconstruction Algorithm in Staging Diagnosis of Bladder Cancer.

Authors:  Kaiyan Hu; Jianping Zhu; Pei Li; Lili Ying
Journal:  Comput Math Methods Med       Date:  2022-06-28       Impact factor: 2.809

3.  SLC14A1 (UT-B) gene rearrangement in urothelial carcinoma of the bladder: a case report.

Authors:  Zhongying Guo; Xiaobing Niu; Guangbo Fu; Baoxue Yang; Guangping Chen; Su'an Sun
Journal:  Diagn Pathol       Date:  2020-07-23       Impact factor: 2.644

Review 4.  REVIEW OF THE BLADDER CANCER MOLECULAR CLASSIFICATION PROPOSED: A NEW ERA - NEW TAXONOMY.

Authors:  Šoip Šoipi; Majda Vučić; Borislav Spajić; Božo Krušlin; Miroslav Tomić; Monika Ulamec
Journal:  Acta Clin Croat       Date:  2022-02       Impact factor: 0.780

5.  Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis.

Authors:  Isabel M Vincent; Rónán Daly; Bertrand Courtioux; Amy M Cattanach; Sylvain Biéler; Joseph M Ndung'u; Sylvie Bisser; Michael P Barrett
Journal:  PLoS Negl Trop Dis       Date:  2016-12-12

6.  Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy.

Authors:  Simeon U Springer; Chung-Hsin Chen; Maria Del Carmen Rodriguez Pena; Lu Li; Christopher Douville; Yuxuan Wang; Joshua David Cohen; Diana Taheri; Natalie Silliman; Joy Schaefer; Janine Ptak; Lisa Dobbyn; Maria Papoli; Isaac Kinde; Bahman Afsari; Aline C Tregnago; Stephania M Bezerra; Christopher VandenBussche; Kazutoshi Fujita; Dilek Ertoy; Isabela W Cunha; Lijia Yu; Trinity J Bivalacqua; Arthur P Grollman; Luis A Diaz; Rachel Karchin; Ludmila Danilova; Chao-Yuan Huang; Chia-Tung Shun; Robert J Turesky; Byeong Hwa Yun; Thomas A Rosenquist; Yeong-Shiau Pu; Ralph H Hruban; Cristian Tomasetti; Nickolas Papadopoulos; Ken W Kinzler; Bert Vogelstein; Kathleen G Dickman; George J Netto
Journal:  Elife       Date:  2018-03-20       Impact factor: 8.140

7.  Global, regional, and national burdens of bladder cancer in 2017: estimates from the 2017 global burden of disease study.

Authors:  Hairong He; Hongjun Xie; Yule Chen; Chengzhuo Li; Didi Han; Fengshuo Xu; Jun Lyu
Journal:  BMC Public Health       Date:  2020-11-11       Impact factor: 3.295
  7 in total

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