| Literature DB >> 26613998 |
Roger E Kelley1, Ramy El-Khoury2.
Abstract
Frontotemporal dementia (FTD) is a not-uncommon explanation for progressive cognitive deficit in patients who often have a genetic susceptibility for such a neurodegenerative process. However, FTD does not seem to identify one particular pathogenetic mechanism but rather a spectrum of pathologies with particular predilection for the frontal and temporal lobes of the brain. There have been various subcategorizations of this form of dementia that have a tendency to be of earlier onset than typical Alzheimer disease and heralded by behavioral or communication manifestations. There is a behavioral variant and a language variant, referred to as primary progressive aphasia.Entities:
Keywords: Abulia; Aphasia neurodegenerative disorder; Behavioral disturbance; Dementia; Disinhibition; Impulsivity; Inattention
Mesh:
Year: 2016 PMID: 26613998 PMCID: PMC5549462 DOI: 10.1016/j.ncl.2015.08.007
Source DB: PubMed Journal: Neurol Clin ISSN: 0733-8619 Impact factor: 3.806