Literature DB >> 2661267

Homology between surface protein antigen genes of Streptococcus sobrinus and Streptococcus mutans.

I Takahashi1, N Okahashi, C Sasakawa, M Yoshikawa, S Hamada, T Koga.   

Abstract

The structural gene (pag gene) for a 210 kDa protein antigen of Streptococcus sobrinus serotype g was cloned and compared with that (pac gene) of a 190 kDa protein antigen of Streptococcus mutans serotype c. Immunodiffusion analysis revealed that the product of the pag gene immunologically cross-reacted with that of the pac gene. Southern blot and nucleotide sequence analyses revealed that a significant homology existed between the middle regions of the two structural genes.

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Year:  1989        PMID: 2661267     DOI: 10.1016/0014-5793(89)80664-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  17 in total

1.  Restriction fragment length polymorphisms and sequence variation within the spaP gene of Streptococcus mutans serotype c isolates.

Authors:  L J Brady; P J Crowley; J K Ma; C Kelly; S F Lee; T Lehner; A S Bleiweis
Journal:  Infect Immun       Date:  1991-05       Impact factor: 3.441

2.  Complete nucleotide sequence of the gene for a surface protein antigen of Streptococcus sobrinus.

Authors:  M Tokuda; N Okahashi; I Takahashi; M Nakai; S Nagaoka; M Kawagoe; T Koga
Journal:  Infect Immun       Date:  1991-09       Impact factor: 3.441

3.  Sequence and structural analysis of surface protein antigen I/II (SpaA) of Streptococcus sobrinus.

Authors:  R J LaPolla; J A Haron; C G Kelly; W R Taylor; C Bohart; M Hendricks; J P Pyati; R T Graff; J K Ma; T Lehner
Journal:  Infect Immun       Date:  1991-08       Impact factor: 3.441

4.  Conservation of the gene encoding streptococcal antigen I/II in oral streptococci.

Authors:  J K Ma; C G Kelly; G Munro; R A Whiley; T Lehner
Journal:  Infect Immun       Date:  1991-08       Impact factor: 3.441

5.  Oral immunization with recombinant Streptococcus lactis carrying the Streptococcus mutans surface protein antigen gene.

Authors:  M Iwaki; N Okahashi; I Takahashi; T Kanamoto; Y Sugita-Konishi; K Aibara; T Koga
Journal:  Infect Immun       Date:  1990-09       Impact factor: 3.441

6.  Oral immunization with recombinant Salmonella typhimurium expressing surface protein antigen A of Streptococcus sobrinus: persistence and induction of humoral responses in rats.

Authors:  T K Redman; C C Harmon; S M Michalek
Journal:  Infect Immun       Date:  1994-08       Impact factor: 3.441

7.  Differentiation of salivary agglutinin-mediated adherence and aggregation of mutans streptococci by use of monoclonal antibodies against the major surface adhesin P1.

Authors:  L J Brady; D A Piacentini; P J Crowley; P C Oyston; A S Bleiweis
Journal:  Infect Immun       Date:  1992-03       Impact factor: 3.441

8.  Identification of monoclonal antibody-binding domains within antigen P1 of Streptococcus mutans and cross-reactivity with related surface antigens of oral streptococci.

Authors:  L J Brady; D A Piacentini; P J Crowley; A S Bleiweis
Journal:  Infect Immun       Date:  1991-12       Impact factor: 3.441

9.  Inactivation of the gene encoding surface protein SspA in Streptococcus gordonii DL1 affects cell interactions with human salivary agglutinin and oral actinomyces.

Authors:  H F Jenkinson; S D Terry; R McNab; G W Tannock
Journal:  Infect Immun       Date:  1993-08       Impact factor: 3.441

10.  Molecular characterization of a negative regulator of Streptococcus sobrinus surface protein antigen gene.

Authors:  I Takahashi; N Okahashi; S Hamada
Journal:  J Bacteriol       Date:  1993-07       Impact factor: 3.490

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