S Alfandari1, J Robert2, Y Péan3, C Rabaud4, J P Bedos5, E Varon6, A Lepape7, J P Bru8, R Gauzit9. 1. Service de réanimation et des maladies infectieuses, centre hospitalier Dron, 59208 Tourcoing, France. Electronic address: Alfandari.s@gmail.com. 2. Bactériologie et hygiène, hôpitaux universitaires de la Pitié-Salpêtrière - Charles-Foix, AP-HP, 75013 Paris, France. 3. Observatoire national de l'épidémiologie de la résistance bactérienne aux antibiotiques (ONERBA), 75006 Paris, France. 4. Service des maladies infectieuses, CHU, 54511 Nancy, France. 5. Service de réanimation, centre hospitalier Henri-Mignot, 78157 Le Chesnay, France. 6. Laboratoire de bactériologie, HEGP, 75908 Paris, France. 7. Service de réanimation, hôpital Sud, 69495 Lyon, France. 8. Service des maladies infectieuses, centre hospitalier de la région d'Annecy, 74374 Annecy, France. 9. Service d'anesthésie-réanimation chirurgicale, CHU Cochin, AP-HP, 75679 Paris, France.
Abstract
OBJECTIVES: We aimed to assess antibiotic prescriptions to identify potential targets for improvement. METHODS: We conducted a point prevalence survey (November 2010) of antibiotic use in 314 voluntary hospitals recruited by the French Infectious Diseases Society (SPILF) and the National Observatory for Epidemiology of Bacterial Resistance to Antimicrobials (ONERBA). Data were entered online, immediately analyzed and exported. RESULTS: The prevalence of antibiotic use was 19.5% (9059/46,446patients). A higher prevalence was observed in the infectious disease (58.4%), hematology (58%), and intensive care (48.7%) units. The three most frequently used antibiotic classes were aminopenicillins (23.8%), fluoroquinolones (17.9%), and 3rd-generation cephalosporins (16.7%). A monotherapy was prescribed to 64% of patients. The reasons for the antibiotic prescription were written in the medical records of 74% of patients and 62% were consistent with the local guidelines. CONCLUSION: Our results are similar to that of other studies. Various local targets for improvement have been identified to help hospitals define a better antibiotic stewardship.
OBJECTIVES: We aimed to assess antibiotic prescriptions to identify potential targets for improvement. METHODS: We conducted a point prevalence survey (November 2010) of antibiotic use in 314 voluntary hospitals recruited by the French Infectious Diseases Society (SPILF) and the National Observatory for Epidemiology of Bacterial Resistance to Antimicrobials (ONERBA). Data were entered online, immediately analyzed and exported. RESULTS: The prevalence of antibiotic use was 19.5% (9059/46,446patients). A higher prevalence was observed in the infectious disease (58.4%), hematology (58%), and intensive care (48.7%) units. The three most frequently used antibiotic classes were aminopenicillins (23.8%), fluoroquinolones (17.9%), and 3rd-generation cephalosporins (16.7%). A monotherapy was prescribed to 64% of patients. The reasons for the antibiotic prescription were written in the medical records of 74% of patients and 62% were consistent with the local guidelines. CONCLUSION: Our results are similar to that of other studies. Various local targets for improvement have been identified to help hospitals define a better antibiotic stewardship.
Authors: Charlotte Jackson; Yingfen Hsia; Julia A Bielicki; Sally Ellis; Peter Stephens; Ian C K Wong; Mike Sharland Journal: BMJ Glob Health Date: 2019-02-27