Valérie Cochen De Cock1, Nicolas Benard-Serre2, Valérie Driss3, Manon Granier2, Mahmoud Charif2, Bertrand Carlander2, Matthieu Desplan4, Muriel Croisier Langenier2, Didier Cugy5, Sophie Bayard6. 1. Pôle Sommeil, Clinique Beau Soleil, Montpellier, France; EuroMov, Laboratoire Movement to Health (M2H), University of Montpellier-1, France; Centre d'Investigation Clinique, Hôpital Saint Eloi, Montpellier, France. Electronic address: valerie.cochen@gmail.com. 2. Service de Neurologie, Hôpital Gui de Chauliac, Montpellier, France. 3. Centre d'Investigation Clinique, Hôpital Saint Eloi, Montpellier, France. 4. Pôle Sommeil, Clinique Beau Soleil, Montpellier, France. 5. Clinique du Sommeil, CHU Pellegrin, Bordeaux, France; Unité Hypnologie et Chronobiologie Clinique, Pavillon de la Mutualité, Pessac, France. 6. Pôle Sommeil, Clinique Beau Soleil, Montpellier, France; EuroMov, Laboratoire Movement to Health (M2H), University of Montpellier-1, France; Centre d'Investigation Clinique, Hôpital Saint Eloi, Montpellier, France.
Abstract
OBJECTIVE: Supine sleep is associated with increased obstructive sleep apnea. People with Parkinson's disease (PD) complain about difficulties turning around in bed. The relationship between supine sleep and sleep-disordered breathing has never been explored in people with Parkinson's disease. METHODS: Fifteen consecutive people with PD with severe Obstructive Sleep Apnea Syndrome (OSAS) were compared to: (1) 15 age-matched, gender-matched, body mass index-matched and Unified Parkinson's Disease Rating Scale-III score-matched people with PD without sleep-disordered breathing; (2) 11 age-matched and gender-matched people with severe obstructive sleep apnea syndrome (OSAS) alone; and (3) 11 age-matched and gender-matched healthy controls. Outcomes were: number of position changes during the night and per hour of sleep, and the percentage of sleep time spent in supine. RESULTS: People with PD and severe OSAS spent most of their sleep time in the supine position (93 ± 11%); while people with PD without OSAS (61 ± 24%, p <0.001), people with isolated, severe OSAS (50 ± 28%, p <0.001), and the controls (40 ± 21, p <0.001) spent significantly less time on their back. People with PD and severe OSAS changed their position in bed per hour of sleep (0.4 ± 0.5) less frequently than those with PD without OSAS (1.1 ± 0.8, p = 0.002), those with isolated OSAS (1.2 ± 1.0, p = 0.006) and the controls (1.5 ± 0.5, p <0.001). CONCLUSION: PD and severe OSAS are associated with a major reduction in the number of position changes and an increased supine sleep position during the night. For people with PD, alleviating the difficulties of turning around in bed might reduce the supine sleep position and improve sleep-disordered breathing.
OBJECTIVE: Supine sleep is associated with increased obstructive sleep apnea. People with Parkinson's disease (PD) complain about difficulties turning around in bed. The relationship between supine sleep and sleep-disordered breathing has never been explored in people with Parkinson's disease. METHODS: Fifteen consecutive people with PD with severe Obstructive Sleep Apnea Syndrome (OSAS) were compared to: (1) 15 age-matched, gender-matched, body mass index-matched and Unified Parkinson's Disease Rating Scale-III score-matched people with PD without sleep-disordered breathing; (2) 11 age-matched and gender-matched people with severe obstructive sleep apnea syndrome (OSAS) alone; and (3) 11 age-matched and gender-matched healthy controls. Outcomes were: number of position changes during the night and per hour of sleep, and the percentage of sleep time spent in supine. RESULTS:People with PD and severe OSAS spent most of their sleep time in the supine position (93 ± 11%); while people with PD without OSAS (61 ± 24%, p <0.001), people with isolated, severe OSAS (50 ± 28%, p <0.001), and the controls (40 ± 21, p <0.001) spent significantly less time on their back. People with PD and severe OSAS changed their position in bed per hour of sleep (0.4 ± 0.5) less frequently than those with PD without OSAS (1.1 ± 0.8, p = 0.002), those with isolated OSAS (1.2 ± 1.0, p = 0.006) and the controls (1.5 ± 0.5, p <0.001). CONCLUSION:PD and severe OSAS are associated with a major reduction in the number of position changes and an increased supine sleep position during the night. For people with PD, alleviating the difficulties of turning around in bed might reduce the supine sleep position and improve sleep-disordered breathing.