Jin-Tao Wu1, De-Yong Long2, Jian-Zeng Dong2, Shan-Ling Wang1, Xian-Wei Fan1, Hai-Tao Yang1, Hong-Yan Duan1, Li-Jie Yan1, Peng Qian1, Chao-Kuan Yang3. 1. Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou, China. 2. Department of Cardiology, Center for Atrial Fibrillation, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. 3. Department of Cardiology, Henan Medical College, Zhengzhou, China. Electronic address: ycksyy@126.com.
Abstract
BACKGROUND: It has been demonstrated that advanced interatrial block (IAB) is associated with an increased risk of atrial fibrillation (AF); however, the impact of advanced IAB on recurrence of paroxysmal AF after catheter ablation is not clear. METHODS: 204 consecutive patients with paroxysmal AF who underwent index circumferential pulmonary vein (PV) isolation were prospectively enrolled. In all patients, a resting electrocardiogram in sinus rhythm was evaluated for the presence of advanced IAB, defined as a P-wave duration >120ms and biphasic (±) morphology in the inferior leads. Advanced IAB was detected in 20.1% of patients. AF recurrence was defined as the occurrence of confirmed atrial tachyarrhythmia lasting more than 30s beyond 3 months after the catheter ablation in the absence of any antiarrhythmic treatment. RESULTS: During the mean follow-up period of 13.9±6.2 months (range, 3-27 months), 62 patients (30.4%) developed recurrence of AF. The recurrence rate was higher in patients with advanced IAB than those without advanced IAB (46.3% vs. 26.4%, p=0.006). Cox regression analysis with adjustment for age, P-wave duration, CHADS2 score, and PV isolation identified advanced IAB (hazard ratio, 2.111; 95% confidence interval, 1.034-4.308; p=0.040) and left atrial diameter (hazard ratio, 1.051; 95% confidence interval, 1.004-1.100; p=0.034) as two independent predictors of recurrence of AF. CONCLUSIONS: Patients with advanced IAB were at an increased risk of AF recurrence after catheter ablation.
BACKGROUND: It has been demonstrated that advanced interatrial block (IAB) is associated with an increased risk of atrial fibrillation (AF); however, the impact of advanced IAB on recurrence of paroxysmal AF after catheter ablation is not clear. METHODS: 204 consecutive patients with paroxysmal AF who underwent index circumferential pulmonary vein (PV) isolation were prospectively enrolled. In all patients, a resting electrocardiogram in sinus rhythm was evaluated for the presence of advanced IAB, defined as a P-wave duration >120ms and biphasic (±) morphology in the inferior leads. Advanced IAB was detected in 20.1% of patients. AF recurrence was defined as the occurrence of confirmed atrial tachyarrhythmia lasting more than 30s beyond 3 months after the catheter ablation in the absence of any antiarrhythmic treatment. RESULTS: During the mean follow-up period of 13.9±6.2 months (range, 3-27 months), 62 patients (30.4%) developed recurrence of AF. The recurrence rate was higher in patients with advanced IAB than those without advanced IAB (46.3% vs. 26.4%, p=0.006). Cox regression analysis with adjustment for age, P-wave duration, CHADS2 score, and PV isolation identified advanced IAB (hazard ratio, 2.111; 95% confidence interval, 1.034-4.308; p=0.040) and left atrial diameter (hazard ratio, 1.051; 95% confidence interval, 1.004-1.100; p=0.034) as two independent predictors of recurrence of AF. CONCLUSIONS:Patients with advanced IAB were at an increased risk of AF recurrence after catheter ablation.
Authors: Antoni Bayés de Luna; Adrian Baranchuk; Manuel Martínez-Sellés; Pyotr G Platonov Journal: Ann Noninvasive Electrocardiol Date: 2016-12-16 Impact factor: 1.468
Authors: Enes E Gul; Raveen Pal; Jane Caldwell; Usama Boles; Wilma Hopman; Benedict Glover; Kevin A Michael; Damian Redfearn; Chris Simpson; Hoshiar Abdollah; Adrian Baranchuk Journal: Ann Noninvasive Electrocardiol Date: 2016-12-25 Impact factor: 1.468
Authors: Göksel Çinier; Ahmet İlker Tekkeşin; Tuğba Yanar Çelik; Özlem Mercan; Halil İbrahim Tanboğa; Muhammed Burak Günay; Ceyhan Türkkan; Mert İlker Hayıroğlu; Bryce Alexander; Ahmet Taha Alper; Adrian Baranchuk Journal: J Atr Fibrillation Date: 2018-10-31