| Literature DB >> 26611657 |
Jillian R Sanzone1, K A Woerpel2.
Abstract
trans-Oxasilacycloheptenes are highly reactive strained alkenes. Competition reactions showed that these seven-membered ring trans-alkenes underwent [4+2] cycloaddition reactions faster than a trans-cyclooctene. They also reacted with quinones and dimethyl acetylenedicarboxylate to form adducts with high diastereoselectivity. Kinetic studies showed that ring strain increases nucleophilicity by approximately 10(9).Entities:
Keywords: alkenes; cycloaddition; cycloheptenes; silicon; strained molecules
Year: 2015 PMID： 26611657 DOI： 10.1002/anie.201510056
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336