Literature DB >> 26611370

Cylindroxanthones A-C, three new xanthones and their cytotoxicity from the stem bark of Garcinia cylindrocarpa.

Edwin Risky Sukandar1, Taslim Ersam2, Sri Fatmawati3, Pongpun Siripong4, Thammarat Aree5, Santi Tip-pyang6.   

Abstract

Three new xanthones, cylindroxanthones A-C (1-3), were isolated from the stem bark of Garcinia cylindrocarpa. The structures were established on the basis of spectroscopic analysis. The molecular structure of 1 was unequivocally confirmed by single-crystal X-ray diffraction analysis. These three xanthones were evaluated regarding their cytotoxicity against KB, HeLa S-3, HT-29, MCF-7, and Hep G2 cancer cell lines. Compound 1 exhibited good cytotoxicity against KB cell with IC50 value of 2.36 μM.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cylindroxanthones A–C; Cytotoxicity; Garcinia cylindrocarpa; Xanthone

Mesh：

Substances：

Year:  2015        PMID： 26611370     DOI： 10.1016/j.fitote.2015.11.017

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  4 in total

1.  Cytotoxic and Anti-Inflammatory Activities of Dihydroisocoumarin and Xanthone Derivatives from Garcinia picrorhiza.

Authors:  Edwin R Sukandar; Sutin Kaennakam; Pia Raab; Xuehong Nöst; Kitiya Rassamee; Rudolf Bauer; Pongpun Siripong; Taslim Ersam; Santi Tip-Pyang; Warinthorn Chavasiri
Journal:  Molecules       Date:  2021-11-01       Impact factor: 4.411

2.  Synergistic interaction of a consortium of the brown-rot fungus Fomitopsis pinicola and the bacterium Ralstonia pickettii for DDT biodegradation.

Authors:  Adi Setyo Purnomo; Atmira Sariwati; Ichiro Kamei
Journal:  Heliyon       Date:  2020-06-07

3.  Acylphloroglucinol Derivatives from Garcinia multiflora with Anti-Inflammatory Effect in LPS-Induced RAW264.7 Macrophages.

Authors:  Lin-Yang Cheng; Yun-Chen Tsai; Shu-Ling Fu; Ming-Jen Cheng; Ping-Jyun Sung; Mei-Ing Chung; Jih-Jung Chen
Journal:  Molecules       Date:  2018-10-10       Impact factor: 4.411

Review 4.  Chemical and Biological Research on Herbal Medicines Rich in Xanthones.

Authors:  Jingya Ruan; Chang Zheng; Yanxia Liu; Lu Qu; Haiyang Yu; Lifeng Han; Yi Zhang; Tao Wang
Journal:  Molecules       Date:  2017-10-11       Impact factor: 4.411
  4 in total

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