Literature DB >> 26610176

Cost-optimization in the treatment of multidrug resistant tuberculosis in Nigeria.

Baba Maiyaki Musa1, Denny John2, Abdulrazaq G Habib3, Andreas Kuznik4.   

Abstract

OBJECTIVE: To compare the cost of facility-based MDR TB care (F) to home-based care (H) from the perspective of the Nigerian national health system.
METHODS: We assessed the expected costs of the two MDR TB treatment approaches using a decision-analytic model with a follow-up of 6 months. MDR TB treatment outcomes were obtained from a systematic review of randomised clinical trials. The outcomes of interest included treatment success, treatment failure, treatment default and mortality and did not vary significantly between the two alternatives. Treatment costs included the cost of the following: drug therapy (F, H), hospital stay (F), nurse care (F, H), physician care (F), nursing facility (F) and transport to the healthcare provider (H). Finally, we estimated the potential cost savings associated with home-based treatment for all patients starting MDR TB treatment in Nigeria.
RESULTS: The average expected total treatment cost for a Nigerian patient treated for MDR TB was estimated at US2095 for facility - based care and 1535 for home-based care, a potential saving of 25%. One of the major drivers of this difference is significantly more intensive, and therefore more costly, nursing care in hospitals. In 2013, a total of 426 patients were initiated on facility-based MDR TB treatment in Nigeria. Thus, the potential savings through home-based care are US$ 223 204 per year.
CONCLUSION: In Nigeria, treatment of MDR TB using home-based care is expected to result in similar patient outcomes at markedly reduced public health costs as facility-based care.
© 2015 John Wiley & Sons Ltd.

Entities:  

Keywords:  Africa; Afrique; Care; Cost-minimisation; Model; cuidados; minimisation des coûts; minimización de costes; modelo; modèle; soins; África

Mesh:

Substances:

Year:  2015        PMID: 26610176     DOI: 10.1111/tmi.12648

Source DB:  PubMed          Journal:  Trop Med Int Health        ISSN: 1360-2276            Impact factor:   2.622


  4 in total

1.  Implementation of multidrug-resistant tuberculosis (MDR-TB) treatment in Gabon: lessons learnt from the field.

Authors:  U Ateba-Ngoa; J R Edoa; B R Adegbite; E G Rossatanga; D Madiou; A Mfoumbi; C Mevyann; P Achimi Agbo; J Mahoumbou; S Gould; B Lell; A A Adegnika; C Köhler; P G Kremsner; M Massinga-Loembe; A Alabi; M P Grobusch
Journal:  Infection       Date:  2019-05-09       Impact factor: 3.553

2.  Cost savings associated with video directly observed therapy for treatment of tuberculosis.

Authors:  C K Lam; K Fluegge; M Macaraig; J Burzynski
Journal:  Int J Tuberc Lung Dis       Date:  2019-11-01       Impact factor: 2.373

Review 3.  Decentralized care for multidrug-resistant tuberculosis: a systematic review and meta-analysis.

Authors:  Jennifer Ho; Anthony L Byrne; Nguyen N Linh; Ernesto Jaramillo; Greg J Fox
Journal:  Bull World Health Organ       Date:  2017-08-01       Impact factor: 9.408

4.  Cost-effectiveness of treating multidrug-resistant tuberculosis in treatment initiative centers and treatment follow-up centers in Ethiopia.

Authors:  Senait Alemayehu; Amanuel Yigezu; Damen Hailemariam; Alemayehu Hailu
Journal:  PLoS One       Date:  2020-07-27       Impact factor: 3.240

  4 in total

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