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Literature DB >> 26608567

Isolation and Characterization of Madariaga Virus from a Horse in Paraíba State, Brazil.

M L C R Silva¹, A J Auguste^2,3, A C B Terzian⁴, D Vedovello⁴, F Riet-Correa⁵, V M K Macário¹, M P G Mourão¹, L S Ullmann⁶, J P Araújo⁶, S C Weaver^2,3, M L Nogueira^1,4.

Abstract

Madariaga virus (MADV), the new species designation for the South American isolates of eastern equine encephalitis virus (EEEV), is genetically divergent and substantially different in ecology and pathogenesis from North American EEEV strains. We isolated and characterized a MADV isolate obtained from a horse in Brazil. Our results support previous phylogenetic studies showing there are three genetically distinct MADV lineages. The MADV isolate from Paraíba State belongs to the South American lineage III and is closely related to Peruvian, Colombian and Venezuelan isolates.

Entities: Chemical Disease Gene Species

Keywords: Alphavirus; Madariaga virus; arboviruses; eastern equine encephalitis virus; horse

Mesh：

Year: 2015 PMID： 26608567 PMCID： PMC4879107 DOI： 10.1111/tbed.12441

Source DB: PubMed Journal: Transbound Emerg Dis ISSN： 1865-1674 Impact factor: 5.005

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