Carolyn Miller Reilly1, Melinda Higgins2, Andrew Smith3, Steven D Culler4, Sandra B Dunbar2. 1. Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA 30322, USA. Electronic address: cmill02@emory.edu. 2. Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA 30322, USA. 3. Emory University School of Medicine, Atlanta, GA 30322, USA. 4. Emory School of Public Health, Atlanta, GA 30322, USA.
Abstract
PURPOSE: This paper presents a secondary in-depth analysis of five persons with heart failure randomized to receive an education and behavioral intervention on fluid restriction as part of a larger study. METHODS: Using a single subject analysis design, time series analyses models were constructed for each of the five patients for a period of 180 days to determine correlations between daily measures of patient reported fluid intake, thoracic impedance, and weights, and relationships between patient reported outcomes of symptom burden and health related quality of life over time. RESULTS: Negative relationships were observed between fluid intake and thoracic impedance, and between impedance and weight, while positive correlations were observed between daily fluid intake and weight. CONCLUSIONS: By constructing time series analyses of daily measures of fluid congestion, trends and patterns of fluid congestion emerged which could be used to guide individualized patient care or future research endeavors. Employment of such a specialized analysis technique allows for the elucidation of clinically relevant findings potentially disguised when only evaluating aggregate outcomes of larger studies.
RCT Entities:
PURPOSE: This paper presents a secondary in-depth analysis of five persons with heart failure randomized to receive an education and behavioral intervention on fluid restriction as part of a larger study. METHODS: Using a single subject analysis design, time series analyses models were constructed for each of the five patients for a period of 180 days to determine correlations between daily measures of patient reported fluid intake, thoracic impedance, and weights, and relationships between patient reported outcomes of symptom burden and health related quality of life over time. RESULTS: Negative relationships were observed between fluid intake and thoracic impedance, and between impedance and weight, while positive correlations were observed between daily fluid intake and weight. CONCLUSIONS: By constructing time series analyses of daily measures of fluid congestion, trends and patterns of fluid congestion emerged which could be used to guide individualized patient care or future research endeavors. Employment of such a specialized analysis technique allows for the elucidation of clinically relevant findings potentially disguised when only evaluating aggregate outcomes of larger studies.
Authors: Mariell Jessup; William T Abraham; Donald E Casey; Arthur M Feldman; Gary S Francis; Theodore G Ganiats; Marvin A Konstam; Donna M Mancini; Peter S Rahko; Marc A Silver; Lynne Warner Stevenson; Clyde W Yancy Journal: Circulation Date: 2009-03-26 Impact factor: 29.690
Authors: Harlan M Krumholz; Joan Amatruda; Grace L Smith; Jennifer A Mattera; Sarah A Roumanis; Martha J Radford; Paula Crombie; Viola Vaccarino Journal: J Am Coll Cardiol Date: 2002-01-02 Impact factor: 24.094
Authors: Carolyn Miller Reilly; Melinda Higgins; Andrew Smith; Steven D Culler; Sandra B Dunbar Journal: Eur J Cardiovasc Nurs Date: 2014-07-02 Impact factor: 3.908