Jane Bell1, Natasha Nassar2, Robin Turner3, Carol Bower4,5, David Gillett6, Wilma McBain6, Camille Raynes-Greenow1. 1. Sydney School of Public Health, University of Sydney, Sydney, New South Wales, Australia. 2. Population Perinatal Health Research, Kolling Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia. 3. School of Public Health and Community Medicine, University of New South Wales, Perth, Western Australia, Australia. 4. Western Australian Register of Developmental Anomalies, King Edward Memorial Hospital, Perth, Western Australia, Australia. 5. Telethon Kids Institute, University of Western Australia, Perth, Western Australia, Australia. 6. Cleft Lip and Palate and Craniomaxillofacial Unit, Princess Margaret Hospital, Perth, Western Australia, Australia.
Abstract
AIM: The aim of this study was to compare hospital admissions from infancy to adulthood, between children born with orofacial clefts (OFC) and those without OFC. METHODS: The method used was a cohort study using record-linked administrative datasets. Participants included all children liveborn in Western Australia (WA) between 1980 and 2010 diagnosed with OFC, who were frequency matched by year of birth to randomly selected liveborn children without OFC. We calculated rate ratios (RR) of hospital admission, number and reason of admissions, cumulative length of stay, for each cleft type (cleft lip only (CLO), cleft lip and palate (CL+P), cleft palate only (CPO), no OFC) and by age period (infancy, pre-school, primary and high school ages, and early adulthood). RESULTS: Overall, 1396 children were diagnosed with an OFC and compared with 6566 children without OFC. Individuals born with OFC were up to three times more likely to be admitted to hospital, had more admissions and longer cumulative length of stay in all age periods. Children with OFC were also more likely to be admitted for ear and digestive system conditions (RR up to 30 and six times higher, respectively). Children with CL+P and CPO were more likely to be admitted for respiratory conditions (RR 1.3-2.0) and children with CPO were six times more likely to be admitted for care for other congenital anomalies. CONCLUSIONS: Throughout childhood, individuals born with OFC were more likely to be admitted, and had more hospitalisations than those without OFC. Children born with CL+P or CPO had a higher hospitalisation burden than children born with CLO.
AIM: The aim of this study was to compare hospital admissions from infancy to adulthood, between children born with orofacial clefts (OFC) and those without OFC. METHODS: The method used was a cohort study using record-linked administrative datasets. Participants included all children liveborn in Western Australia (WA) between 1980 and 2010 diagnosed with OFC, who were frequency matched by year of birth to randomly selected liveborn children without OFC. We calculated rate ratios (RR) of hospital admission, number and reason of admissions, cumulative length of stay, for each cleft type (cleft lip only (CLO), cleft lip and palate (CL+P), cleft palate only (CPO), no OFC) and by age period (infancy, pre-school, primary and high school ages, and early adulthood). RESULTS: Overall, 1396 children were diagnosed with an OFC and compared with 6566 children without OFC. Individuals born with OFC were up to three times more likely to be admitted to hospital, had more admissions and longer cumulative length of stay in all age periods. Children with OFC were also more likely to be admitted for ear and digestive system conditions (RR up to 30 and six times higher, respectively). Children with CL+P and CPO were more likely to be admitted for respiratory conditions (RR 1.3-2.0) and children with CPO were six times more likely to be admitted for care for other congenital anomalies. CONCLUSIONS: Throughout childhood, individuals born with OFC were more likely to be admitted, and had more hospitalisations than those without OFC. Children born with CL+P or CPO had a higher hospitalisation burden than children born with CLO.
Authors: Nelangi M Pinto; Richard Nelson; Lorenzo Botto; Michael D Puchalski; Sergey Krikov; Jaewhan Kim; Norman J Waitzman Journal: Birth Defects Res Date: 2017-02-13 Impact factor: 2.344