Literature DB >> 26607272

Short Communication: HIV-1 Infection Suppresses Circulating Viral Restriction microRNAs.

Yu Zhou1,2, Li Sun1, Xu Wang2, Hao Liang3, Li Ye3, Li Zhou1, Bing-Yu Liang3, Jie-Liang Li2, Man-Qing Liu4, Jin-Song Peng4, Dun-Jin Zhou4, Xi-En Gui5, Wen-Zhe Ho1,2.   

Abstract

MicroRNAs (miRNAs) participate in host innate immunity against HIV-1 infection. We examined the impact of HIV-1 infection on viral restriction miRNAs in plasma of HIV-1-infected subjects. HIV-1-infected subjects had significantly lower plasma levels of HIV-1 restriction miRNAs (miRs-29a, -29b, -125b, -223, -198, and -382) than control subjects. Further in vitro studies showed that HIV-1 infection of macrophages suppressed production of the extracellular miRs-29b, -125b, and -223. These data demonstrate the compelling evidence that HIV-1 infection impairs host innate immunity by inhibiting antiviral miRNAs, which provide a possible mechanism for HIV-1 persistence in the host.

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Year:  2015        PMID： 26607272      PMCID： PMC4817567          DOI： 10.1089/AID.2015.0253

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  16 in total

1.  Suppression of microRNA-silencing pathway by HIV-1 during virus replication.

Authors:  Robinson Triboulet; Bernard Mari; Yea-Lih Lin; Christine Chable-Bessia; Yamina Bennasser; Kevin Lebrigand; Bruno Cardinaud; Thomas Maurin; Pascal Barbry; Vincent Baillat; Jacques Reynes; Pierre Corbeau; Kuan-Teh Jeang; Monsef Benkirane
Journal:  Science       Date:  2007-02-22       Impact factor: 47.728

Review 2.  MicroRNAs and HIV-1: complex interactions.

Authors:  Zachary Klase; Laurent Houzet; Kuan-Teh Jeang
Journal:  J Biol Chem       Date:  2012-10-05       Impact factor: 5.157

Review 3.  Extracellular communication via microRNA: lipid particles have a new message.

Authors:  Katey J Rayner; Elizabeth J Hennessy
Journal:  J Lipid Res       Date:  2013-03-15       Impact factor: 5.922

4.  MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response.

Authors:  Muller Fabbri; Alessio Paone; Federica Calore; Roberta Galli; Eugenio Gaudio; Ramasamy Santhanam; Francesca Lovat; Paolo Fadda; Charlene Mao; Gerard J Nuovo; Nicola Zanesi; Melissa Crawford; Gulcin H Ozer; Dorothee Wernicke; Hansjuerg Alder; Michael A Caligiuri; Patrick Nana-Sinkam; Danilo Perrotti; Carlo M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-02       Impact factor: 11.205

5.  A critical function of toll-like receptor-3 in the induction of anti-human immunodeficiency virus activities in macrophages.

Authors:  Yu Zhou; Xu Wang; Manqing Liu; Quan Hu; Li Song; Li Ye; Dunjin Zhou; Wenzhe Ho
Journal:  Immunology       Date:  2010-07-16       Impact factor: 7.397

6.  MicroRNA binding to the HIV-1 Gag protein inhibits Gag assembly and virus production.

Authors:  Antony K Chen; Prabuddha Sengupta; Kayoko Waki; Schuyler B Van Engelenburg; Takahiro Ochiya; Sherimay D Ablan; Eric O Freed; Jennifer Lippincott-Schwartz
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-17       Impact factor: 11.205

7.  Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients.

Authors:  Kenneth W Witwer; Andria K Watson; Joel N Blankson; Janice E Clements
Journal:  Retrovirology       Date:  2012-01-12       Impact factor: 4.602

8.  MicroRNA-150 is a potential biomarker of HIV/AIDS disease progression and therapy.

Authors:  Saif Ullah Munshi; Harekrushna Panda; Prasida Holla; Bharat Bhushan Rewari; Shahid Jameel
Journal:  PLoS One       Date:  2014-05-14       Impact factor: 3.240

9.  MicroRNAs differentially present in the plasma of HIV elite controllers reduce HIV infection in vitro.

Authors:  Rita Reynoso; Natalia Laufer; Matthias Hackl; Susanna Skalicky; Rossella Monteforte; Gabriela Turk; Mauricio Carobene; Jorge Quarleri; Pedro Cahn; Roland Werner; Heribert Stoiber; Regina Grillari-Voglauer; Johannes Grillari
Journal:  Sci Rep       Date:  2014-08-01       Impact factor: 4.379

Review 10.  miRNAs as non-invasive biomarkers for lung cancer diagnosis.

Authors:  Paola Ulivi; Wainer Zoli
Journal:  Molecules       Date:  2014-06-17       Impact factor: 4.411
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  3 in total

1.  Polymorphisms in miRNAs Gene (146a, 149, 196a) and Susceptibility to ARV-associated Hepatotoxicity.

Authors:  Hari Om Singh; Sushma Jadhav; Dharmesh Samani; Tapan N Dhole
Journal:  Curr Genomics       Date:  2019-02       Impact factor: 2.236

2.  Army liposome formulation containing QS-21 render human monocyte-derived macrophages less permissive to HIV-1 infection by upregulating ABOBEC3A.

Authors:  Ousman Jobe; Jiae Kim; Daniel O Pinto; Zuzana Villar; Tiffany Hewitt; Elizabeth H Duncan; Alexander Anderson; Neelakshi Gohain; Hua Gong; Courtney Tucker; Carl R Alving; Gary R Matyas; Elke Bergmann-Leitner; Mangala Rao
Journal:  Sci Rep       Date:  2022-05-09       Impact factor: 4.996

Review 3.  The Regulatory Roles of MicroRNAs in Bone Remodeling and Perspectives as Biomarkers in Osteoporosis.

Authors:  Mengge Sun; Xiaoya Zhou; Lili Chen; Shishu Huang; Victor Leung; Nan Wu; Haobo Pan; Wanxin Zhen; William Lu; Songlin Peng
Journal:  Biomed Res Int       Date:  2016-03-17       Impact factor: 3.411
  3 in total

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