Literature DB >> 26605985

Ligand-Controlled Diastereoselective 1,3-Dipolar Cycloadditions of Azomethine Ylides with Methacrylonitrile.

Mary C Walton1, Yun-Fang Yang2, Xin Hong2, K N Houk2, Larry E Overman1.   

Abstract

Copper-catalyzed reactions of glycine ester arylimines and methacrylonitrile provide selective access to either the endo or exo pyrrolidine cycloadducts. DFT calculations have elucidated the origins of ligand-controlled diastereoselectivity.

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Year:  2015        PMID: 26605985     DOI: 10.1021/acs.orglett.5b03171

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  General Pyrrolidine Synthesis via Iridium-Catalyzed Reductive Azomethine Ylide Generation from Tertiary Amides and Lactams.

Authors:  Ken Yamazaki; Pablo Gabriel; Graziano Di Carmine; Julia Pedroni; Mirxan Farizyan; Trevor A Hamlin; Darren J Dixon
Journal:  ACS Catal       Date:  2021-06-09       Impact factor: 13.084

  1 in total

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