Literature DB >> 26604162

Can Helminth Infection Reverse Microbial Dysbiosis?

P'ng Loke1, Yvonne A L Lim2.   

Abstract

There is growing interest in treating inflammatory conditions with helminth infection. Recently, Loukas and colleagues have reported promising results from using experimental hookworm infection to reduce gluten sensitivity in celiac disease patients. Analysis of microbiota samples from the trial is contributing to our understanding of the complexity underlying helminth–microbiota–host relationships.

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Year:  2015        PMID: 26604162      PMCID: PMC4752385          DOI: 10.1016/j.pt.2015.10.001

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN: 1471-4922


  10 in total

1.  Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease.

Authors:  John Croese; Paul Giacomin; Severine Navarro; Andrew Clouston; Leisa McCann; Annette Dougall; Ivana Ferreira; Atik Susianto; Peter O'Rourke; Mariko Howlett; James McCarthy; Christian Engwerda; Dianne Jones; Alex Loukas
Journal:  J Allergy Clin Immunol       Date:  2014-09-20       Impact factor: 10.793

2.  Autoimmunity: The worm returns.

Authors:  Joel V Weinstock
Journal:  Nature       Date:  2012-11-08       Impact factor: 49.962

3.  Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon.

Authors:  Mara Jana Broadhurst; Amir Ardeshir; Bittoo Kanwar; Julie Mirpuri; Uma Mahesh Gundra; Jacqueline M Leung; Kirsten E Wiens; Ivan Vujkovic-Cvijin; Charlie C Kim; Felix Yarovinsky; Nicholas W Lerche; Joseph M McCune; P'ng Loke
Journal:  PLoS Pathog       Date:  2012-11-15       Impact factor: 6.823

4.  Effect of hookworm infection on wheat challenge in celiac disease--a randomised double-blinded placebo controlled trial.

Authors:  A James Daveson; Dianne M Jones; Soraya Gaze; Henry McSorley; Andrew Clouston; Andrew Pascoe; Sharon Cooke; Richard Speare; Graeme A Macdonald; Robert Anderson; James S McCarthy; Alex Loukas; John Croese
Journal:  PLoS One       Date:  2011-03-08       Impact factor: 3.240

5.  Chronic Trichuris muris Infection Decreases Diversity of the Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli.

Authors:  Jacob Bak Holm; Daniel Sorobetea; Pia Kiilerich; Yuliaxis Ramayo-Caldas; Jordi Estellé; Tao Ma; Lise Madsen; Karsten Kristiansen; Marcus Svensson-Frej
Journal:  PLoS One       Date:  2015-05-05       Impact factor: 3.240

6.  Interactions between multiple helminths and the gut microbiota in wild rodents.

Authors:  Jakub Kreisinger; Géraldine Bastien; Heidi C Hauffe; Julian Marchesi; Sarah E Perkins
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-08-19       Impact factor: 6.237

7.  Patent human infections with the whipworm, Trichuris trichiura, are not associated with alterations in the faecal microbiota.

Authors:  Philip Cooper; Alan W Walker; Jorge Reyes; Martha Chico; Susannah J Salter; Maritza Vaca; Julian Parkhill
Journal:  PLoS One       Date:  2013-10-04       Impact factor: 3.240

8.  Helminth colonization is associated with increased diversity of the gut microbiota.

Authors:  Soo Ching Lee; Mei San Tang; Yvonne A L Lim; Seow Huey Choy; Zachary D Kurtz; Laura M Cox; Uma Mahesh Gundra; Ilseung Cho; Richard Bonneau; Martin J Blaser; Kek Heng Chua; P'ng Loke
Journal:  PLoS Negl Trop Dis       Date:  2014-05-22

9.  Experimental hookworm infection: a randomized placebo-controlled trial in asthma.

Authors:  J R Feary; A J Venn; K Mortimer; A P Brown; D Hooi; F H Falcone; D I Pritchard; J R Britton
Journal:  Clin Exp Allergy       Date:  2009-12-16       Impact factor: 5.018

10.  Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects.

Authors:  Paul Giacomin; Martha Zakrzewski; John Croese; Xiaopei Su; Javier Sotillo; Leisa McCann; Severine Navarro; Makedonka Mitreva; Lutz Krause; Alex Loukas; Cinzia Cantacessi
Journal:  Sci Rep       Date:  2015-09-18       Impact factor: 4.379

  10 in total
  7 in total

1.  Schistosoma mansoni Worm Infection Regulates the Intestinal Microbiota and Susceptibility to Colitis.

Authors:  Achilleas Floudas; Gabriella Aviello; Christian Schwartz; Ian B Jeffery; Paul W O'Toole; Padraic G Fallon
Journal:  Infect Immun       Date:  2019-07-23       Impact factor: 3.441

Review 2.  Helminths and intestinal barrier function.

Authors:  Derek M McKay; Adam Shute; Fernando Lopes
Journal:  Tissue Barriers       Date:  2017-01-02

3.  The gut microbiota response to helminth infection depends on host sex and genotype.

Authors:  Fei Ling; Natalie Steinel; Jesse Weber; Lei Ma; Chris Smith; Decio Correa; Bin Zhu; Daniel Bolnick; Gaoxue Wang
Journal:  ISME J       Date:  2020-01-31       Impact factor: 10.302

4.  The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.

Authors:  Neima Briggs; Jill Weatherhead; K Jagannadha Sastry; Peter J Hotez
Journal:  PLoS Negl Trop Dis       Date:  2016-09-15

5.  Reduced microbial diversity in adult survivors of childhood acute lymphoblastic leukemia and microbial associations with increased immune activation.

Authors:  Ling Ling Chua; Reena Rajasuriar; Mohamad Shafiq Azanan; Noor Kamila Abdullah; Mei San Tang; Soo Ching Lee; Yin Ling Woo; Yvonne Ai Lian Lim; Hany Ariffin; P'ng Loke
Journal:  Microbiome       Date:  2017-03-20       Impact factor: 14.650

Review 6.  The interplay of helminthic neuropeptides and proteases in parasite survival and host immunomodulation.

Authors:  Rimanpreet Kaur; Naina Arora; Meera G Nair; Amit Prasad
Journal:  Biochem Soc Trans       Date:  2022-02-28       Impact factor: 4.919

7.  Dietary Inulin and Trichuris suis Infection Promote Beneficial Bacteria Throughout the Porcine Gut.

Authors:  Sophie Stolzenbach; Laura J Myhill; Lee O'Brien Andersen; Lukasz Krych; Helena Mejer; Andrew R Williams; Peter Nejsum; C Rune Stensvold; Dennis S Nielsen; Stig M Thamsborg
Journal:  Front Microbiol       Date:  2020-03-04       Impact factor: 5.640

  7 in total

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