Literature DB >> 26603856

Degradable Magnetic Composites for Minimally Invasive Interventions: Device Fabrication, Targeted Drug Delivery, and Cytotoxicity Tests.

Christian Peters1, Marcus Hoop2, Salvador Pané2, Bradley J Nelson2, Christofer Hierold1.   

Abstract

Superparamagnetic nanoparticles and a functional, degradable polymer matrix based on poly(ethylene glycol) are combined to enable fully degradable magnetic microdevices for minimally invasive biomedical applications. A bioinspired helical microrobot platform mimicking Escherichia coli bacteria is fabricated and actuated using weak rotating magnetic fields. Locomotion based on corkscrew propulsion, targeted drug delivery, and low-degradation-product cytotoxicity are demonstrated.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  cytotoxicity; degradable composites; superparamagnetic particles; swimming microrobots; targeted drug delivery

Mesh：

Substances：

Year:  2015        PMID： 26603856     DOI： 10.1002/adma.201503112

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  16 in total

1.  Micro/Nanorobots for Biomedicine: Delivery, Surgery, Sensing, and Detoxification.

Authors:  Jinxing Li; Berta Esteban-Fernández de Ávila; Wei Gao; Liangfang Zhang; Joseph Wang
Journal:  Sci Robot       Date:  2017-03-01

2.  Functionalized 3D Architected Materials via Thiol-Michael Addition and Two-Photon Lithography.

Authors:  Daryl W Yee; Michael D Schulz; Robert H Grubbs; Julia R Greer
Journal:  Adv Mater       Date:  2017-02-20       Impact factor: 30.849

Review 3.  Magnetic Soft Materials and Robots.

Authors:  Yoonho Kim; Xuanhe Zhao
Journal:  Chem Rev       Date:  2022-02-01       Impact factor: 72.087

4.  Hydrophobicity Influence on Swimming Performance of Magnetically Driven Miniature Helical Swimmers.

Authors:  Chengwei Ye; Jia Liu; Xinyu Wu; Ben Wang; Li Zhang; Yuanyi Zheng; Tiantian Xu
Journal:  Micromachines (Basel)       Date:  2019-03-06       Impact factor: 2.891

5.  Shaping the Assembly of Superparamagnetic Nanoparticles.

Authors:  Minghan Hu; Hans-Jürgen Butt; Katharina Landfester; Markus B Bannwarth; Sanghyuk Wooh; Héloïse Thérien-Aubin
Journal:  ACS Nano       Date:  2019-03-01       Impact factor: 15.881

6.  A Microstirring Pill Enhances Bioavailability of Orally Administered Drugs.

Authors:  Rodolfo Mundaca-Uribe; Emil Karshalev; Berta Esteban-Fernández de Ávila; Xiaoli Wei; Bryan Nguyen; Irene Litvan; Ronnie H Fang; Liangfang Zhang; Joseph Wang
Journal:  Adv Sci (Weinh)       Date:  2021-05-18       Impact factor: 16.806

7.  Fabrication and Characterization of a Magnetic Drilling Actuator for Navigation in a Three-dimensional Phantom Vascular Network.

Authors:  Sunkey Lee; Seungmin Lee; Sangwon Kim; Chang-Hwan Yoon; Hun-Jun Park; Jin-Young Kim; Hongsoo Choi
Journal:  Sci Rep       Date:  2018-02-27       Impact factor: 4.379

8.  Magnetically tunable bidirectional locomotion of a self-assembled nanorod-sphere propeller.

Authors:  José García-Torres; Carles Calero; Francesc Sagués; Ignacio Pagonabarraga; Pietro Tierno
Journal:  Nat Commun       Date:  2018-04-25       Impact factor: 14.919

9.  Bacteria-inspired nanorobots with flagellar polymorphic transformations and bundling.

Authors:  Jamel Ali; U Kei Cheang; James D Martindale; Mehdi Jabbarzadeh; Henry C Fu; Min Jun Kim
Journal:  Sci Rep       Date:  2017-10-26       Impact factor: 4.379

Review 10.  Frontiers of Medical Micro/Nanorobotics: in vivo Applications and Commercialization Perspectives Toward Clinical Uses.

Authors:  Fernando Soto; Robert Chrostowski
Journal:  Front Bioeng Biotechnol       Date:  2018-11-14
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