Literature DB >> 26602411

Evaluation for abdominal aortic aneurysms is justified in patients with thoracic aortic aneurysms.

Mariana R DeFreitas1, Leslie E Quint2,3, Kuanwong Watcharotone4, Bin Nan5, Michael J Ranella6, Joanna R Hider6, Peter S Liu7, David M Williams7, Jonathan L Eliason8, Himanshu J Patel9.   

Abstract

Aortic aneurysms are a significant cause of mortality, and the presence of multiple aneurysms may affect treatment plans. The purpose of this study was to determine the frequency of abdominal aortic aneurysms (AAAs) in patients with thoracic aortic aneurysms (TAAs) and to establish whether patient specific factors, such as gender and comorbidities, influenced the frequency of AAAs, thereby indicating if and when abdominal aortic evaluation is justified. Electronic medical records were reviewed from 1000 patients with a computed tomography (CT) angiogram of the chest and abdomen and a clinical diagnosis of TAA from Cardiac Surgery clinic between 2008 and 2013. 538 patients with history of aortic intervention, dissection, rupture or trauma were excluded. The frequency of AAAs among the 462 remaining patients was established, and statistical analysis was used to elucidate differences in frequency based on age, gender, comorbidities, and TAA location. Overall, 104 of 462 (22.5 %) patients with a TAA also had an AAA. There were significant differences in the frequency of AAA based on TAA location, age, and comorbidities. The following comorbidities showed positive associations with AAA using logistic regression analysis: age ≥65 (P < 0.0001; OR 30.1; CI 7.14-126.61), smoking history (P < 0.0001; OR 4.1; 2.35-7.30), and hypertension (P = 0.024; OR 2.1; CI 1.11-4.16). Aneurysms in the proximal/mid descending (P < 0.0001; OR 4.96; CI 2.32-10.61) and diaphragm level (P < 0.0001; OR 38.4; CI 14.71-100.15) of the aorta also showed a positive association with AAAs when adjusted for age and gender. AAA screening in patients with TAA is a reasonable, evidence-based option regardless of the TAA location, with the strongest support in patients >age 55, with systemic hypertension, a smoking history and/or a TAA in the descending thoracic aorta.

Entities:  

Keywords:  Aneurysm (abdominal aorta thoracic aorta); Aorta/aortic; Computed tomography; Imaging

Mesh:

Year:  2015        PMID: 26602411     DOI: 10.1007/s10554-015-0807-7

Source DB:  PubMed          Journal:  Int J Cardiovasc Imaging        ISSN: 1569-5794            Impact factor:   2.357


  19 in total

1.  Synchronous and metachronous thoracic aneurysms in patients with abdominal aortic aneurysms.

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Journal:  J Vasc Surg       Date:  2012-06-22       Impact factor: 4.268

Review 2.  Thoracic and abdominal aortic aneurysms.

Authors:  Eric M Isselbacher
Journal:  Circulation       Date:  2005-02-15       Impact factor: 29.690

3.  High frequency of thoracic aneurysms in patients with abdominal aortic aneurysms.

Authors:  Emma Larsson; Lia Vishnevskaya; Bo Kalin; Fredrik Granath; Jesper Swedenborg; Rebecka Hultgren
Journal:  Ann Surg       Date:  2011-01       Impact factor: 12.969

4.  Incidence of aortic complications in patients with bicuspid aortic valves.

Authors:  Hector I Michelena; Amber D Khanna; Douglas Mahoney; Edit Margaryan; Yan Topilsky; Rakesh M Suri; Ben Eidem; William D Edwards; Thoralf M Sundt; Maurice Enriquez-Sarano
Journal:  JAMA       Date:  2011-09-14       Impact factor: 56.272

Review 5.  Abdominal aortic aneurysm.

Authors:  N Sakalihasan; R Limet; O D Defawe
Journal:  Lancet       Date:  2005 Apr 30-May 6       Impact factor: 79.321

6.  Abnormal extracellular matrix protein transport associated with increased apoptosis of vascular smooth muscle cells in marfan syndrome and bicuspid aortic valve thoracic aortic aneurysm.

Authors:  Maria Nataatmadja; Malcolm West; Jenny West; Kim Summers; Philip Walker; Michio Nagata; Teruo Watanabe
Journal:  Circulation       Date:  2003-09-09       Impact factor: 29.690

7.  Distribution, determinants, and normal reference values of thoracic and abdominal aortic diameters by computed tomography (from the Framingham Heart Study).

Authors:  Ian S Rogers; Joseph M Massaro; Quynh A Truong; Amir A Mahabadi; Matthias F Kriegel; Caroline S Fox; George Thanassoulis; Eric M Isselbacher; Udo Hoffmann; Christopher J O'Donnell
Journal:  Am J Cardiol       Date:  2013-03-13       Impact factor: 2.778

8.  Improved prognosis of thoracic aortic aneurysms: a population-based study.

Authors:  W D Clouse; J W Hallett; H V Schaff; M M Gayari; D M Ilstrup; L J Melton
Journal:  JAMA       Date:  1998-12-09       Impact factor: 56.272

9.  Proximal thoracic aortic diameter measurements at CT: repeatability and reproducibility according to measurement method.

Authors:  Leslie E Quint; Peter S Liu; Anna M Booher; Kuanwong Watcharotone; James D Myles
Journal:  Int J Cardiovasc Imaging       Date:  2012-08-03       Impact factor: 2.357

10.  Risk factors for abdominal aortic aneurysms: a 7-year prospective study: the Tromsø Study, 1994-2001.

Authors:  Signe Helene Forsdahl; Kulbir Singh; Steinar Solberg; Bjarne K Jacobsen
Journal:  Circulation       Date:  2009-04-13       Impact factor: 29.690

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  6 in total

Review 1.  Cardiovascular imaging 2015 in the International Journal of Cardiovascular Imaging.

Authors:  Hiram G Bezerra; Ricardo A Costa; Johan H C Reiber; Paul Schoenhagen; Arthur A Stillman; Johan De Sutter; Nico R L Van de Veire
Journal:  Int J Cardiovasc Imaging       Date:  2016-05       Impact factor: 2.357

2.  Population based ultrasonographic screening of abdominal aortic aneurysms.

Authors:  Prabhakar Rajiah; Johan H C Reiber; Sasan Partovi
Journal:  Int J Cardiovasc Imaging       Date:  2016-07-27       Impact factor: 2.357

3.  Pelvic artery aneurysm screening provides value in patients with thoracic aortic aneurysms.

Authors:  Matthew Chapman; Leslie E Quint; Kuanwong Watcharotone; Bin Nan; Michael J Ranella; Mariana R DeFreitas; Joanna R Hider; Jonathan L Eliason; Himanshu J Patel
Journal:  Int J Cardiovasc Imaging       Date:  2017-05-27       Impact factor: 2.357

4.  Increased risk of deep vein thrombosis and pulmonary thromboembolism in patients with aortic aneurysms: A nationwide cohort study.

Authors:  Feng-You Lee; Wei-Kung Chen; Chun-Hsiang Chiu; Cheng-Li Lin; Chia-Hung Kao; Chao-Hsien Chen; Tse-Yen Yang; Ching-Yuan Lai
Journal:  PLoS One       Date:  2017-06-07       Impact factor: 3.240

5.  Inflammation and TGF-β Signaling Differ between Abdominal Aneurysms and Occlusive Disease.

Authors:  A IJpma; L Te Riet; K M van de Luijtgaarden; P M van Heijningen; J Burger; D Majoor-Krakauer; E V Rouwet; J Essers; H J M Verhagen; I van der Pluijm
Journal:  J Cardiovasc Dev Dis       Date:  2019-11-01

6.  Bioinformatics analysis of common key genes and pathways of intracranial, abdominal, and thoracic aneurysms.

Authors:  Siwei Bi; Ruiqi Liu; Linfeng He; Jingyi Li; Jun Gu
Journal:  BMC Cardiovasc Disord       Date:  2021-01-06       Impact factor: 2.298

  6 in total

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