B Mitchell1, C Chong2, W K Lim2. 1. Department of Medicine, Gold Coast University Hospital, Gold Coast, Queensland, Australia. 2. Department of Aged Care, Northern Hospital, Melbourne, Victoria, Australia.
Abstract
BACKGROUND: The rate of medication non-adherence has been consistently reported to be between 20 and 50%. The majority of available data comes from international studies, and we hypothesised that a similar rate of adherence may be observed in Australian patients. AIMS: To determine the rate of adherence to medications after discharge from acute general hospital admission and identify factors that may be associated with non-adherence. METHODS: A prospective cohort study of 68 patients, comparing admission and discharge medication regimens to self-reported regimens 30-40 days after discharge from hospital. Patients were followed up via telephone call and univariate and multivariate binary logistic regression used to determine patient factors associated with non-adherence. RESULTS: In all, 27 of 68 patients (39.7%) were non-adherent to one or more regular medications at follow up. Intentional and unintentional non-adherence contributed equally to non-adherence. Using multivariate analysis, presence of a carer responsible for medications was associated with significantly lower non-adherence (odds ratio (OR) 0.20 (0.05-0.83), P = 0.027) when adjusted for age, co-morbidities, chemist blister pack and total number of discharge medications. CONCLUSIONS: Non-adherence to prescription medications is suboptimal and consistent with previous overseas studies. Having a carer responsible for medications is associated with significantly lower rates of non-adherence. Understanding patients' preferences and involving them in their healthcare may reduce intentional non-adherence.
BACKGROUND: The rate of medication non-adherence has been consistently reported to be between 20 and 50%. The majority of available data comes from international studies, and we hypothesised that a similar rate of adherence may be observed in Australian patients. AIMS: To determine the rate of adherence to medications after discharge from acute general hospital admission and identify factors that may be associated with non-adherence. METHODS: A prospective cohort study of 68 patients, comparing admission and discharge medication regimens to self-reported regimens 30-40 days after discharge from hospital. Patients were followed up via telephone call and univariate and multivariate binary logistic regression used to determine patient factors associated with non-adherence. RESULTS: In all, 27 of 68 patients (39.7%) were non-adherent to one or more regular medications at follow up. Intentional and unintentional non-adherence contributed equally to non-adherence. Using multivariate analysis, presence of a carer responsible for medications was associated with significantly lower non-adherence (odds ratio (OR) 0.20 (0.05-0.83), P = 0.027) when adjusted for age, co-morbidities, chemist blister pack and total number of discharge medications. CONCLUSIONS: Non-adherence to prescription medications is suboptimal and consistent with previous overseas studies. Having a carer responsible for medications is associated with significantly lower rates of non-adherence. Understanding patients' preferences and involving them in their healthcare may reduce intentional non-adherence.
Authors: Loes J M van Herpen-Meeuwissen; Hein A W van Onzenoort; Patricia M L A van den Bemt; Barbara Maat; Bart J F van den Bemt Journal: Patient Prefer Adherence Date: 2022-09-28 Impact factor: 2.314