| Literature DB >> 26599987 |
Boryana E Avramova1, Tanya Hristova, Maya Yordanova, Irena Vlahova, Albena Muchinova, Veneta Bojinova, Dobrin Konstantinov.
Abstract
We report a rare case of cerebellar degeneration as a paraneoplastic syndrome in an 8-year-old boy with Hodgkin lymphoma that presented during first-line treatment. Antibodies against Purkinje cells (anti-Tr antibodies) were detected in the serum of the patient. After successful treatment of the lymphoma, the cerebellar symptoms resolved partially. Childhood presentation of paraneoplastic cerebellar degeneration is extremely rare, with only a few reports in the literature. For this reason, the description of all such cases contributes to the enrichment of the medical knowledge and will improve the diagnosis and the treatment of this complication.Entities:
Mesh:
Year: 2016 PMID: 26599987 DOI: 10.1097/MPH.0000000000000486
Source DB: PubMed Journal: J Pediatr Hematol Oncol ISSN: 1077-4114 Impact factor: 1.289