Literature DB >> 26599987

Cerebellar Degeneration as a Rare Paraneoplastic Syndrome in a Child With Hodgkin Lymphoma.

Boryana E Avramova1, Tanya Hristova, Maya Yordanova, Irena Vlahova, Albena Muchinova, Veneta Bojinova, Dobrin Konstantinov.   

Abstract

We report a rare case of cerebellar degeneration as a paraneoplastic syndrome in an 8-year-old boy with Hodgkin lymphoma that presented during first-line treatment. Antibodies against Purkinje cells (anti-Tr antibodies) were detected in the serum of the patient. After successful treatment of the lymphoma, the cerebellar symptoms resolved partially. Childhood presentation of paraneoplastic cerebellar degeneration is extremely rare, with only a few reports in the literature. For this reason, the description of all such cases contributes to the enrichment of the medical knowledge and will improve the diagnosis and the treatment of this complication.

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Year:  2016        PMID: 26599987     DOI: 10.1097/MPH.0000000000000486

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN: 1077-4114            Impact factor:   1.289


  2 in total

1.  The Clinical Spectrum of Autoimmune-Mediated Neurological Diseases in Paediatric Population.

Authors:  Karol Lubarski; Anna Mania; Sławomir Michalak; Krystyna Osztynowicz; Katarzyna Mazur-Melewska; Magdalena Figlerowicz
Journal:  Brain Sci       Date:  2022-04-29

2.  A Case of Paraneoplastic Cerebellar Degeneration that Preceded the Diagnosis of Classical Hodgkin's Lymphoma by 16 Months.

Authors:  Nerea Arratibel; Eduardo Sobejano; Jose Carlos Moran; Luis G Diaz; Almudena Blázquez; Mónica Baile; Álvaro Veiga; Maria Dolores Caballero; Ramón García-Sanz
Journal:  Am J Case Rep       Date:  2020-06-23
  2 in total

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