Literature DB >> 26598694

Smart nanosystems: Bio-inspired technologies that interact with the host environment.

Ester J Kwon1, Justin H Lo2, Sangeeta N Bhatia3.   

Abstract

Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: (i) those that sense the host environment and respond and (ii) those that first prime the host environment to interact with engineered nanoparticles. Smart nanosystems have the potential to produce personalized diagnostic and therapeutic schema by using the local environment to drive material behavior and ultimately improve human health.

Entities:  

Keywords:  cancer nanotechnology; environment-responsive; host priming; nanosystems; smart nanomaterials

Mesh：

Year:  2015        PMID： 26598694      PMCID： PMC4664363          DOI： 10.1073/pnas.1508522112

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  66 in total

1.  pH-Responsive Polymer Microspheres: Rapid Release of Encapsulated Material within the Range of Intracellular pH Financial support was provided by the NSF (Cooperative Agreement No. ECC9843342 to the MIT Biotechnology Process Engineering Center), the NIH (GM26698), and the Department of the Army (Cooperative Agreement DAMD 17-99-2-9-001 to the Center for Innovative Minimally Invasive Therapy). D.M.L. wishes to thank the NIH for a Postdoctoral Fellowship (NRSA Fellowship No. 1 F32 GM20227-01). Scanning electron microscopy and confocal microscopy images were acquired by William Fowle at the Northeastern University Center for Electron Microscopy. Dr. David Putnam, David Ting, and Tommy Thomas are thanked for helpful discussions.

Authors:  David M. Lynn; Mansoor M. Amiji; Robert Langer
Journal:  Angew Chem Int Ed Engl       Date:  2001-05-04       Impact factor: 15.336

2.  Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction.

Authors:  Jiqiu Chen; Ching-Hsuan Tung; Jennifer R Allport; Si Chen; Ralph Weissleder; Paul L Huang
Journal:  Circulation       Date:  2005-04-04       Impact factor: 29.690

3.  Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system.

Authors:  Shiladitya Sengupta; David Eavarone; Ishan Capila; Ganlin Zhao; Nicki Watson; Tanyel Kiziltepe; Ram Sasisekharan
Journal:  Nature       Date:  2005-07-28       Impact factor: 49.962

4.  Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs. 1. In vitro evaluations.

Authors:  Dinesh Shenoy; Steven Little; Robert Langer; Mansoor Amiji
Journal:  Mol Pharm       Date:  2005 Sep-Oct       Impact factor: 4.939

5.  Tumor imaging by means of proteolytic activation of cell-penetrating peptides.

Authors:  Tao Jiang; Emilia S Olson; Quyen T Nguyen; Melinda Roy; Patricia A Jennings; Roger Y Tsien
Journal:  Proc Natl Acad Sci U S A       Date:  2004-12-15       Impact factor: 11.205

6.  Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter.

Authors:  Benedict Law; Alejandro Curino; Thomas H Bugge; Ralph Weissleder; Ching-Hsuan Tung
Journal:  Chem Biol       Date:  2004-01

7.  In vivo imaging of tumors with protease-activated near-infrared fluorescent probes.

Authors:  R Weissleder; C H Tung; U Mahmood; A Bogdanov
Journal:  Nat Biotechnol       Date:  1999-04       Impact factor: 54.908

8.  Integrin-mediated targeting of drug delivery to irradiated tumor blood vessels.

Authors:  Dennis Hallahan; Ling Geng; Shimian Qu; Christopher Scarfone; Todd Giorgio; Edwin Donnelly; Xiang Gao; Jeff Clanton
Journal:  Cancer Cell       Date:  2003-01       Impact factor: 31.743

Review 9.  Hypoglycemia in diabetes.

Authors:  Philip E Cryer; Stephen N Davis; Harry Shamoon
Journal:  Diabetes Care       Date:  2003-06       Impact factor: 19.112

10.  Noninvasive detection of clinically occult lymph-node metastases in prostate cancer.

Authors:  Mukesh G Harisinghani; Jelle Barentsz; Peter F Hahn; Willem M Deserno; Shahin Tabatabaei; Christine Hulsbergen van de Kaa; Jean de la Rosette; Ralph Weissleder
Journal:  N Engl J Med       Date:  2003-06-19       Impact factor: 91.245
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  16 in total

1.  A Synthetic-Biology-Inspired Therapeutic Strategy for Targeting and Treating Hepatogenous Diabetes.

Authors:  Shuai Xue; Jianli Yin; Jiawei Shao; Yuanhuan Yu; Linfeng Yang; Yidan Wang; Mingqi Xie; Martin Fussenegger; Haifeng Ye
Journal:  Mol Ther       Date:  2017-02-01       Impact factor: 11.454

2.  Redox-Responsive Nanoparticle-Mediated Systemic RNAi for Effective Cancer Therapy.

Authors:  Xiaoding Xu; Jun Wu; Shuaishuai Liu; Phei Er Saw; Wei Tao; Yujing Li; Lisa Krygsman; Srinivasan Yegnasubramanian; Angelo M De Marzo; Jinjun Shi; Charles J Bieberich; Omid C Farokhzad
Journal:  Small       Date:  2018-09-17       Impact factor: 13.281

Review 3.  Nanomaterial-Enabled Cancer Therapy.

Authors:  Sabina Quader; Kazunori Kataoka
Journal:  Mol Ther       Date:  2017-05-19       Impact factor: 11.454

Review 4.  Bio-inspired nanomedicine strategies for artificial blood components.

Authors:  Anirban Sen Gupta
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2017-03-15

5.  Renal clearable catalytic gold nanoclusters for in vivo disease monitoring.

Authors:  Colleen N Loynachan; Ava P Soleimany; Jaideep S Dudani; Yiyang Lin; Adrian Najer; Ahmet Bekdemir; Qu Chen; Sangeeta N Bhatia; Molly M Stevens
Journal:  Nat Nanotechnol       Date:  2019-09-02       Impact factor: 39.213

6.  Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections.

Authors:  Ester J Kwon; Matthew Skalak; Alessandro Bertucci; Gary Braun; Francesco Ricci; Erkki Ruoslahti; Michael J Sailor; Sangeeta N Bhatia
Journal:  Adv Mater       Date:  2017-07-12       Impact factor: 30.849

Review 7.  Nanomedicine for Acute Brain Injuries: Insight from Decades of Cancer Nanomedicine.

Authors:  Rebecca M Kandell; Lauren E Waggoner; Ester J Kwon
Journal:  Mol Pharm       Date:  2020-06-25       Impact factor: 4.939

8.  Synthesis, Characterization, and In Vitro Studies of an Reactive Oxygen Species (ROS)-Responsive Methoxy Polyethylene Glycol-Thioketal-Melphalan Prodrug for Glioblastoma Treatment.

Authors:  Natalia Oddone; Frank Boury; Emmanuel Garcion; Andreas M Grabrucker; M Carmen Martinez; Federica Da Ros; Anna Janaszewska; Flavio Forni; Maria Angela Vandelli; Giovanni Tosi; Barbara Ruozi; Jason T Duskey
Journal:  Front Pharmacol       Date:  2020-05-04       Impact factor: 5.810

Review 9.  Activity-Based Diagnostics: An Emerging Paradigm for Disease Detection and Monitoring.

Authors:  Ava P Soleimany; Sangeeta N Bhatia
Journal:  Trends Mol Med       Date:  2020-04-05       Impact factor: 11.951

Review 10.  Bio-Nanocarriers for Lung Cancer Management: Befriending the Barriers.

Authors:  Shruti Rawal; Mayur Patel
Journal:  Nanomicro Lett       Date:  2021-06-12
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