D Michelet1, A Ricbourg2, C Gosme3, M Rossignol4, P Schurando4, E Barranger2, A Mebazaa5, E Gayat6. 1. Department of Anesthesiology, Robert-Debré University Hospital, Assistance publique-Hôpitaux de Paris, 75010 Paris, France; University Paris Diderot, Paris, France. 2. University Paris Diderot, Paris, France; Department of Obstetrics and Gynecology, Saint-Louis-Lariboisière University Hospital, Assistance publique-Hôpitaux de Paris, 75010 Paris, France. 3. Department of Anesthesiology and Intensive Care, Saint-Louis-Lariboisière University Hospital, Assistance publique-Hôpitaux de Paris, 75010 Paris, France. 4. University Paris Diderot, Paris, France; Department of Anesthesiology and Intensive Care, Saint-Louis-Lariboisière University Hospital, Assistance publique-Hôpitaux de Paris, 75010 Paris, France. 5. University Paris Diderot, Paris, France; Department of Anesthesiology and Intensive Care, Saint-Louis-Lariboisière University Hospital, Assistance publique-Hôpitaux de Paris, 75010 Paris, France; UMR-S 942, Inserm, 75010 Paris, France. 6. University Paris Diderot, Paris, France; Department of Anesthesiology and Intensive Care, Saint-Louis-Lariboisière University Hospital, Assistance publique-Hôpitaux de Paris, 75010 Paris, France; UMR-S 942, Inserm, 75010 Paris, France. Electronic address: etienne.gayat@lrb.aphp.fr.
Abstract
BACKGROUND: Emergency postpartum hysterectomy (EPH) is usually considered the final resort for the management of postpartum hemorrhage (PPH). The aim of this observational study was to identify the risk factors for EPH, to evaluate the ability of EPH to stop bleeding and, finally, to estimate its psychological impact. METHODS: This was a retrospective analysis of postpartum hysterectomy in all patients with PPH admitted between 2004 and 2011 to Lariboisière Hospital. We compared women for whom EPH was successful and those who required an advanced interventional procedure (AIP) to stop the bleeding despite hysterectomy. We also evaluated the severe PPH (SPPH) score in this particular setting. The psychological impact of emergency hysterectomy was also assessed. RESULTS: A total of 44 hysterectomies were performed among 869 cases of PPH. Twenty were successful, while an additional AIP was required in 22 others (50%). Prothrombin time<50% and a shorter interval between the onset of PPH and hysterectomy were independently associated with the need for an additional AIP. The area under the ROC curve of the SPPH score to predict the need for another AIP was 0.738 (95% confidence interval 0.548-0.748). Furthermore, 64% of the hysterectomized patients suffered from post-traumatic stress disorder. CONCLUSION: Failure of postpartum hysterectomy to control bleeding was frequent, and it was associated with persistence of coagulopathy. Hysterectomy in this context had important psychological impacts.
BACKGROUND: Emergency postpartum hysterectomy (EPH) is usually considered the final resort for the management of postpartum hemorrhage (PPH). The aim of this observational study was to identify the risk factors for EPH, to evaluate the ability of EPH to stop bleeding and, finally, to estimate its psychological impact. METHODS: This was a retrospective analysis of postpartum hysterectomy in all patients with PPH admitted between 2004 and 2011 to Lariboisière Hospital. We compared women for whom EPH was successful and those who required an advanced interventional procedure (AIP) to stop the bleeding despite hysterectomy. We also evaluated the severe PPH (SPPH) score in this particular setting. The psychological impact of emergency hysterectomy was also assessed. RESULTS: A total of 44 hysterectomies were performed among 869 cases of PPH. Twenty were successful, while an additional AIP was required in 22 others (50%). Prothrombin time<50% and a shorter interval between the onset of PPH and hysterectomy were independently associated with the need for an additional AIP. The area under the ROC curve of the SPPH score to predict the need for another AIP was 0.738 (95% confidence interval 0.548-0.748). Furthermore, 64% of the hysterectomized patients suffered from post-traumatic stress disorder. CONCLUSION: Failure of postpartum hysterectomy to control bleeding was frequent, and it was associated with persistence of coagulopathy. Hysterectomy in this context had important psychological impacts.