Literature DB >> 26597000

An age of enlightenment for cilia: The FASEB summer research conference on the "Biology of Cilia and Flagella".

Pamela V Tran1, Karl F Lechtreck2.   

Abstract

From July 19-24, 2015, 169 clinicians and basic scientists gathered in the vertiginous heights of Snowmass, Colorado (2502 m) for the fourth FASEB summer research conference on the 'Biology of Cilia and Flagella'. Organizers Maureen Barr (Rutgers University), Iain Drummond (Massachusetts General Hospital/Harvard Medical School), and Jagesh Shah (Brigham and Women's Hospital/Harvard Medical School) assembled a program filled with new data and forward-thinking ideas documenting the ongoing growth of the field. Sixty oral presentations and 77 posters covered novel aspects of cilia structure, ciliogenesis, cilia motility, cilia-mediated signaling, and cilia-related disease. In this report, we summarize the meeting, highlight exciting developments and discuss open questions.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Arl13b; Arl3; Axoneme; Bardet–Biedl syndrome (BBS); Calcium; Ciliary membrane; Ciliopathy; Craniofacial defects; Diabetes; Dynein; GPCR; Hedgehog signaling; Intraflagellar transport (IFT); Motility; NPHP; Obesity; Phosphoinositide; Polycystin; Transition zone; Tubulin

Mesh:

Year:  2015        PMID: 26597000      PMCID: PMC4724515          DOI: 10.1016/j.ydbio.2015.10.030

Source DB:  PubMed          Journal:  Dev Biol        ISSN: 0012-1606            Impact factor:   3.582


  21 in total

1.  Altered trafficking and stability of polycystins underlie polycystic kidney disease.

Authors:  Yiqiang Cai; Sorin V Fedeles; Ke Dong; Georgia Anyatonwu; Tamehito Onoe; Michihiro Mitobe; Jian-Dong Gao; Dayne Okuhara; Xin Tian; Anna-Rachel Gallagher; Zhangui Tang; Xiaoli Xie; Maria D Lalioti; Ann-Hwee Lee; Barbara E Ehrlich; Stefan Somlo
Journal:  J Clin Invest       Date:  2014-11-03       Impact factor: 14.808

2.  The ultrastructure of the Chlamydomonas reinhardtii basal apparatus: identification of an early marker of radial asymmetry inherent in the basal body.

Authors:  Stefan Geimer; Michael Melkonian
Journal:  J Cell Sci       Date:  2004-05-11       Impact factor: 5.285

3.  Primary cilia enhance kisspeptin receptor signaling on gonadotropin-releasing hormone neurons.

Authors:  Andrew I Koemeter-Cox; Thomas W Sherwood; Jill A Green; Robert A Steiner; Nicolas F Berbari; Bradley K Yoder; Alexander S Kauffman; Paula C Monsma; Anthony Brown; Candice C Askwith; Kirk Mykytyn
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-30       Impact factor: 11.205

4.  Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

Authors:  You Li; Nikolai T Klena; George C Gabriel; Xiaoqin Liu; Andrew J Kim; Kristi Lemke; Yu Chen; Bishwanath Chatterjee; William Devine; Rama Rao Damerla; Chienfu Chang; Hisato Yagi; Jovenal T San Agustin; Mohamed Thahir; Shane Anderton; Caroline Lawhead; Anita Vescovi; Herbert Pratt; Judy Morgan; Leslie Haynes; Cynthia L Smith; Janan T Eppig; Laura Reinholdt; Richard Francis; Linda Leatherbury; Madhavi K Ganapathiraju; Kimimasa Tobita; Gregory J Pazour; Cecilia W Lo
Journal:  Nature       Date:  2015-03-25       Impact factor: 49.962

5.  DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome.

Authors:  Gisela G Slaats; Joshua C Saldivar; Julien Bacal; Michelle K Zeman; Andrew C Kile; Ann Marie Hynes; Shalabh Srivastava; Jekaterina Nazmutdinova; Krista den Ouden; Miriam S Zagers; Veronica Foletto; Marianne C Verhaar; Colin Miles; John A Sayer; Karlene A Cimprich; Rachel H Giles
Journal:  J Clin Invest       Date:  2015-08-24       Impact factor: 14.808

6.  Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling.

Authors:  Francesc R Garcia-Gonzalo; Siew C Phua; Elle C Roberson; Galo Garcia; Monika Abedin; Stéphane Schurmans; Takanari Inoue; Jeremy F Reiter
Journal:  Dev Cell       Date:  2015-08-24       Impact factor: 12.270

7.  Endothelial cilia are essential for developmental vascular integrity in zebrafish.

Authors:  Sowjanya Kallakuri; Jianxin A Yu; Jade Li; Yuanyuan Li; Brant M Weinstein; Stefania Nicoli; Zhaoxia Sun
Journal:  J Am Soc Nephrol       Date:  2014-09-11       Impact factor: 10.121

8.  Molecular basis of tubulin transport within the cilium by IFT74 and IFT81.

Authors:  Sagar Bhogaraju; Lukas Cajanek; Cécile Fort; Thierry Blisnick; Kristina Weber; Michael Taschner; Naoko Mizuno; Stefan Lamla; Philippe Bastin; Erich A Nigg; Esben Lorentzen
Journal:  Science       Date:  2013-08-30       Impact factor: 47.728

9.  Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents.

Authors:  Jantje M Gerdes; Sonia Christou-Savina; Yan Xiong; Tilo Moede; Noah Moruzzi; Patrick Karlsson-Edlund; Barbara Leibiger; Ingo B Leibiger; Claes-Göran Östenson; Philip L Beales; Per-Olof Berggren
Journal:  Nat Commun       Date:  2014-11-06       Impact factor: 14.919

10.  Primary cilia are specialized calcium signalling organelles.

Authors:  Markus Delling; Paul G DeCaen; Julia F Doerner; Sebastien Febvay; David E Clapham
Journal:  Nature       Date:  2013-12-12       Impact factor: 49.962

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.