Literature DB >> 26596787

Inflammasome assembly: The wheels are turning.

Petr Broz1.   

Abstract

Inflammasomes control host cell death and inflammation in response to sterile or infectious stimuli. Two recent reports published in Science reveal the structural basis for the assembly of NAIP-NLRC4 inflammasomes.

Entities:  

Year:  2015        PMID: 26596787      PMCID: PMC4670994          DOI: 10.1038/cr.2015.137

Source DB:  PubMed          Journal:  Cell Res        ISSN: 1001-0602            Impact factor:   25.617


  11 in total

1.  Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.

Authors:  Els F Halff; Christoph A Diebolder; Marian Versteeg; Arie Schouten; T Harma C Brondijk; Eric G Huizinga
Journal:  J Biol Chem       Date:  2012-09-25       Impact factor: 5.157

2.  The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.

Authors:  Alberto Baroja-Mazo; Fatima Martín-Sánchez; Ana I Gomez; Carlos M Martínez; Joaquín Amores-Iniesta; Vincent Compan; Maria Barberà-Cremades; Jordi Yagüe; Estibaliz Ruiz-Ortiz; Jordi Antón; Segundo Buján; Isabelle Couillin; David Brough; Juan I Arostegui; Pablo Pelegrín
Journal:  Nat Immunol       Date:  2014-06-22       Impact factor: 25.606

3.  The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

Authors:  Yue Zhao; Jieling Yang; Jianjin Shi; Yi-Nan Gong; Qiuhe Lu; Hao Xu; Liping Liu; Feng Shao
Journal:  Nature       Date:  2011-09-14       Impact factor: 49.962

4.  Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes.

Authors:  Jeannette L Tenthorey; Eric M Kofoed; Matthew D Daugherty; Harmit S Malik; Russell E Vance
Journal:  Mol Cell       Date:  2014-03-20       Impact factor: 17.970

5.  Crystal structure of NLRC4 reveals its autoinhibition mechanism.

Authors:  Zehan Hu; Chuangye Yan; Peiyuan Liu; Zhiwei Huang; Rui Ma; Chenlu Zhang; Ruiyong Wang; Yueteng Zhang; Fabio Martinon; Di Miao; Haiteng Deng; Jiawei Wang; Junbiao Chang; Jijie Chai
Journal:  Science       Date:  2013-06-13       Impact factor: 47.728

6.  Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.

Authors:  Liman Zhang; Shuobing Chen; Jianbin Ruan; Jiayi Wu; Alexander B Tong; Qian Yin; Yang Li; Liron David; Alvin Lu; Wei Li Wang; Carolyn Marks; Qi Ouyang; Xinzheng Zhang; Youdong Mao; Hao Wu
Journal:  Science       Date:  2015-10-08       Impact factor: 47.728

7.  Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.

Authors:  Eric M Kofoed; Russell E Vance
Journal:  Nature       Date:  2011-08-28       Impact factor: 49.962

8.  An inherited mutation in NLRC4 causes autoinflammation in human and mice.

Authors:  Akiko Kitamura; Yuki Sasaki; Takaya Abe; Hirotsugu Kano; Koji Yasutomo
Journal:  J Exp Med       Date:  2014-11-10       Impact factor: 14.307

9.  An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome.

Authors:  Scott W Canna; Adriana A de Jesus; Sushanth Gouni; Stephen R Brooks; Bernadette Marrero; Yin Liu; Michael A DiMattia; Kristien J M Zaal; Gina A Montealegre Sanchez; Hanna Kim; Dawn Chapelle; Nicole Plass; Yan Huang; Alejandro V Villarino; Angelique Biancotto; Thomas A Fleisher; Joseph A Duncan; John J O'Shea; Susanne Benseler; Alexei Grom; Zuoming Deng; Ronald M Laxer; Raphaela Goldbach-Mansky
Journal:  Nat Genet       Date:  2014-09-14       Impact factor: 38.330

10.  Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation.

Authors:  Neil Romberg; Khatoun Al Moussawi; Carol Nelson-Williams; Amy L Stiegler; Erin Loring; Murim Choi; John Overton; Eric Meffre; Mustafa K Khokha; Anita J Huttner; Brian West; Nikolai A Podoltsev; Titus J Boggon; Barbara I Kazmierczak; Richard P Lifton
Journal:  Nat Genet       Date:  2014-09-14       Impact factor: 38.330

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  2 in total

Review 1.  Inflammasome Contribution to the Activation of Th1, Th2, and Th17 Immune Responses.

Authors:  Ekaterina Martynova; Albert Rizvanov; Richard A Urbanowicz; Svetlana Khaiboullina
Journal:  Front Microbiol       Date:  2022-03-17       Impact factor: 5.640

2.  Baicalin suppresses NLRP3 inflammasome and nuclear factor-kappa B (NF-κB) signaling during Haemophilus parasuis infection.

Authors:  Shulin Fu; Lei Xu; Sali Li; Yinsheng Qiu; Yu Liu; Zhongyuan Wu; Chun Ye; Yongqing Hou; Chien-An Andy Hu
Journal:  Vet Res       Date:  2016-08-08       Impact factor: 3.683

  2 in total

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