| Literature DB >> 26596579 |
Phillip S Adams1, Antonio Cassara2.
Abstract
Polyuria related to pharmacologic α2-adrenoreceptor agonism has been well described in vitro and in animal models and is thought to be the result of functional antagonism of arginine vasopressin. Despite its widespread use as a sedative and anesthetic adjunct, very few reports of dexmedetomidine-related polyuria in humans exist in the literature. We present the first description of a pediatric patient manifesting polyuria and hypernatremia in association with dexmedetomidine infusion for posterior spinal fusion.Entities:
Keywords: Dexmedetomidine; Pediatric; Polyuria
Mesh:
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Year: 2015 PMID: 26596579 DOI: 10.1007/s00540-015-2101-1
Source DB: PubMed Journal: J Anesth ISSN: 0913-8668 Impact factor: 2.078