| Literature DB >> 26594817 |
Qinnan Yang1, Lingfang Wang1, Jianxue Gao1, Xiaobo Liu1, Yuqing Feng1, Qian Wu1, Allah Bux Baloch1, Lu Cui1, Xiaodong Xia1.
Abstract
Pomegranate rind has been found to inhibit numerous pathogens, mostly attributed to its tannin fraction. The present study was conducted to investigate the quorum sensing (QS) inhibition effect of tannin-rich fraction from pomegranate rind (TFPR) by using an indicator strain Chromobacterium violaceum. Meanwhile, its effect on biofilm formation and motility of Escherichia coli was evaluated. It was shown that TFPR inhibited QS-regulated violacein pigment production. Biofilm formation and motility of E. coli were also hindered by TFPR. Transcriptional analysis further showed that TFPR repressed expressions of curli genes (csgB and csgD) and various motility genes (fimA, fimH, flhD, motB, qseB, and qseC). Our findings indicated that TFPR has potential application for controlling E. coli contaminations or biofilms in the food industry.Entities:
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Year: 2015 PMID： 26594817 DOI： 10.1089/fpd.2015.2027
Source DB: PubMed Journal: Foodborne Pathog Dis ISSN： 1535-3141 Impact factor: 3.171