Literature DB >> 26591741

Dermatological malignancies at a University Teaching Hospital in north-western Tanzania: a retrospective review of 154 cases.

Phillipo L Chalya1, Japhet M Gilyoma, Emmanuel S Kanumba, Brian Mawala, Nestory Masalu, Kahima J Kahima, Peter Rambau.   

Abstract

Dermatological malignancies are among the most common form of cancers and the global incidence has been increasing at an alarming rate. A retrospective study was conducted to determine the prevalence, histopathological pattern, anatomical distribution and treatment outcome of dermatological malignancies at Bugando Medical Centre in North-western Tanzania. Data were collected from patients' files kept in the Medical record department; the surgical wards, operating theatre and histopathology laboratory and analyzed using Statistical package for social sciences system. A total of 154 patients with a histopathological diagnosis of dermatological malignancy were studied. Generally, males outnumbered females by a ratio of 1.4:1. The majority of patients were in the 5th and 6th decades of life. Malignant melanoma was the most common dermatological malignancy (67.5%) followed by Kaposi's sarcoma (10.4%), Squamous cell carcinoma (8.4%) and Basal cell carcinoma (7.8%). The lower limbs were the most frequent site accounting for 55.8%. Wide local excision was the most common surgical procedure performed in 79.2% of cases. Post-operative wound infection was the most common complication in 58.3% of patients. Mortality rate was 3.8%. Dermatological malignancies are more prevalent in our setting. A high index of suspicion is needed to avoid labelling malignancies "chronic ulcers" and all suspected lesions should be biopsed.

Entities:  

Mesh:

Year:  2012        PMID: 26591741     DOI: 10.4314/thrb.v14i1.3

Source DB:  PubMed          Journal:  Tanzan J Health Res        ISSN: 1821-9241


  7 in total

1.  Kaposi's sarcoma: a 10-year experience with 248 patients at a single tertiary care hospital in Tanzania.

Authors:  Phillipo L Chalya; Fidelis Mbunda; Peter F Rambau; Hyasinta Jaka; Nestory Masalu; Mariam Mirambo; Martha F Mushi; Samuel E Kalluvya
Journal:  BMC Res Notes       Date:  2015-09-15

2.  Skin cancers among Albinos at a University teaching hospital in Northwestern Tanzania: a retrospective review of 64 cases.

Authors:  Joseph B Mabula; Phillipo L Chalya; Mabula D Mchembe; Hyasinta Jaka; Geofrey Giiti; Peter Rambau; Nestory Masalu; Erasmus Kamugisha; Ssentongo Robert; Japhet M Gilyoma
Journal:  BMC Dermatol       Date:  2012-06-08

3.  Experiences with surgical treatment of chronic lower limb ulcers at a tertiary hospital in northwestern Tanzania: a prospective review of 300 cases.

Authors:  Fidelis Mbunda; Mabula D McHembe; Phillipo L Chalya; Peter Rambau; Stephen E Mshana; Benson R Kidenya; Japhet M Gilyoma
Journal:  BMC Dermatol       Date:  2012-09-28

4.  Epidemiological and histopathological profile of malignant melanoma in Malawi.

Authors:  Maurice Mulenga; Nathan D Montgomery; Maganizo Chagomerana; Tenganawo Mzumala; Tamiwe Tomoka; Coxcilly Kampani; Yuri Fedoriw; Satish Gopal; Lisbet Sviland
Journal:  BMC Clin Pathol       Date:  2019-04-02

5.  Immunohistochemical Analysis of BRAF (V600E) Mutation and P16 Expression in Malignant Melanoma in Lagos, Nigeria: A 10-Year Retrospective Study.

Authors:  O Obadofin; K Badmos; N Orsi; M Bipin; O Rotimi; A Banjo
Journal:  J Skin Cancer       Date:  2019-04-17

6.  Prevalence of Squamous and Basal Cell Carcinomas in African Albino Skin Cancer Lesions: A Systematic Review and Meta-Analysis of Proportion.

Authors:  Nnaemeka T Onyishi; Samuel R Ohayi
Journal:  J Skin Cancer       Date:  2022-08-30

7.  Clinicopathological correlation of malignant skin tumors: A retrospective study of 5 years.

Authors:  Rahul Rajbhar; Arti Anvikar; Kalpana Sulhyan
Journal:  Int J Health Sci (Qassim)       Date:  2020 May-Jun
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.