Literature DB >> 26590709

Cancer Cells Hijack Gluconeogenic Enzymes to Fuel Cell Growth.

Eduardo Balsa-Martinez1, Pere Puigserver2.   

Abstract

In this issue and the October 15th issue of Molecular Cell, studies by Montal et al. (2015) and Vincent et al. (2015) report that certain types of cancer cells utilize the gluconeogenic enzymes phosphoenolpyruvate carboxykinase (PEPCK) and phosphoenolpyruvate carboxykinase 2 (PCK2) to reprogram anabolic metabolism and support cell growth.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 26590709     DOI： 10.1016/j.molcel.2015.11.005

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  15 in total

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4.  Tissue-Specific Downregulation of Fatty Acid Synthase Suppresses Intestinal Adenoma Formation via Coordinated Reprograming of Transcriptome and Metabolism in the Mouse Model of Apc-Driven Colorectal Cancer.

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Review 7.  The Metabolic Fates of Pyruvate in Normal and Neoplastic Cells.

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10.  Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer.

Authors:  Cindy Hodakoski; Benjamin D Hopkins; Guoan Zhang; Taojunfeng Su; Zhe Cheng; Roxanne Morris; Kyu Y Rhee; Marcus D Goncalves; Lewis C Cantley
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