Literature DB >> 2659062

Lipopolysaccharide-induced insulin resistance in monolayers of cultured hepatocytes.

M T Portolés1, R Pagani, M J Ainaga, I Díaz-Laviada, A M Municio.   

Abstract

In order to clarify the endotoxin effect on the hepatic removal of insulin, the influence of lipopolysaccharide (LPS) from E. coli 0111:B4 on the insulin binding and endocytosis in cultured hepatocytes from adult male rats has been investigated. LPS decreases both processes in a time and temperature-dependent manner, showing a major effect at short time and low temperature, according to the characteristics of LPS binding and uptake.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2659062      PMCID： PMC2040547     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  15 in total

1.  Blood insulin responses to blood glucose levels in high output sepsis and spetic shock.

Authors:  G H Clowes; H Martin; S Walji; E Hirsch; R Gazitua; R Goodfellow
Journal:  Am J Surg       Date:  1978-04       Impact factor: 2.565

2.  Impaired gluconeogenesis in dogs with E. coli bacteremia.

Authors:  A C Groves; L I Woolf; P J O'Regan; C Beach; C Hasinoff; W H Sutherland
Journal:  Surgery       Date:  1974-10       Impact factor: 3.982

3.  The internalisation of [125I] insulin by isolated rat hepatocytes.

Authors:  G P Poole; C I Pogson; K J O'Connor; N R Lazarus
Journal:  Horm Metab Res       Date:  1982-10       Impact factor: 2.936

4.  Surface binding and rates of internalization of 125I-insulin in adipocytes and IM-9 lymphocytes.

Authors:  J M Olefsky; M Kao
Journal:  J Biol Chem       Date:  1982-08-10       Impact factor: 5.157

5.  Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

Authors:  H T Haigler; F R Maxfield; M C Willingham; I Pastan
Journal:  J Biol Chem       Date:  1980-02-25       Impact factor: 5.157

6.  On the mechanism of ligand-induced down-regulation of insulin receptor level in the liver cell.

Authors:  M Krupp; M D Lane
Journal:  J Biol Chem       Date:  1981-02-25       Impact factor: 5.157

7.  Fluid endocytosis in isolated rat parenchymal and non-parenchymal liver cells.

Authors:  L Ose; T Ose; R Reinertsen; T Berg
Journal:  Exp Cell Res       Date:  1980-03       Impact factor: 3.905

8.  The hepatic failure of sepsis: cellular versus substrate.

Authors:  F B Cerra; J H Siegel; J R Border; J Wiles; R R McMenamy
Journal:  Surgery       Date:  1979-09       Impact factor: 3.982

9.  Hyperinsulinism in endotoxin shock dogs.

Authors:  W G Blackard; J H Anderson; J J Spitzer
Journal:  Metabolism       Date:  1976-06       Impact factor: 8.694

10.  Effect of Escherichia coli lipopolysaccharide on the microviscosity of liver plasma membranes and hepatocyte suspensions and monolayers.

Authors:  M T Portolés; R Pagani; I Díaz-Laviada; A M Municio
Journal:  Cell Biochem Funct       Date:  1987-01       Impact factor: 3.685
View more
  3 in total

1.  Binding studies and localization of Escherichia coli lipopolysaccharide in cultured hepatocytes by an immunocolloidal-gold technique.

Authors:  I Díaz-Laviada; J Ainaga; M T Portolés; J L Carrascosa; A M Muncio; R Pagani
Journal:  Histochem J       Date:  1991-05

2.  Effect of insulin levels on the phosphorylation of specific amino acid residues in IRS-1: implications for burn-induced insulin resistance.

Authors:  Xiao-Ming Lu; Victoria F Hamrahi; Ronald G Tompkins; Alan J Fischman
Journal:  Int J Mol Med       Date:  2009-10       Impact factor: 4.101

3.  Hepatic expression of lipopolysaccharide-binding protein (Lbp) is induced by the gut microbiota through Myd88 and impairs glucose tolerance in mice independent of obesity.

Authors:  Antonio Molinaro; Ara Koh; Hao Wu; Marc Schoeler; Maria Ilaria Faggi; Alba Carreras; Anna Hallén; Fredrik Bäckhed; Robert Caesar
Journal:  Mol Metab       Date:  2020-04-16       Impact factor: 7.422
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.