Literature DB >> 26589914

Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells.

Anna Parente-Ribes1, Sigrid S Skånland2, Simone Bürgler3, Audun Os1, Dong Wang1, Bjarne Bogen4, Geir E Tjønnfjord5, Kjetil Taskén6, Ludvig A Munthe7.   

Abstract

Entities:  

Keywords:  CD40L (CD154); cancer microenvironment; chronic lymphocytic leukemia; small molecular pathway inhibitors

Mesh:

Substances:

Year:  2015        PMID: 26589914      PMCID: PMC4938324          DOI: 10.3324/haematol.2015.135590

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


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  15 in total

1.  B-chronic lymphocytic leukemia: a malignancy of anti-self B cells.

Authors:  F Caligaris-Cappio
Journal:  Blood       Date:  1996-04-01       Impact factor: 22.113

2.  Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-γ by a T-bet-dependent mechanism.

Authors:  Simone Bürgler; Aleix Gimeno; Anna Parente-Ribes; Dong Wang; Audun Os; Stephen Devereux; Peter Jebsen; Bjarne Bogen; Geir E Tjønnfjord; Ludvig A Munthe
Journal:  J Immunol       Date:  2014-12-10       Impact factor: 5.422

Review 3.  CD40-CD40 ligand.

Authors:  C van Kooten; J Banchereau
Journal:  J Leukoc Biol       Date:  2000-01       Impact factor: 4.962

4.  T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses.

Authors:  Sigrid S Skånland; Kristine Moltu; Torunn Berge; Einar M Aandahl; Kjetil Taskén
Journal:  Biochem J       Date:  2014-06-15       Impact factor: 3.857

5.  Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.

Authors:  Antonella Contri; Anna Maria Brunati; Livio Trentin; Anna Cabrelle; Marta Miorin; Luca Cesaro; Lorenzo A Pinna; Renato Zambello; Gianpietro Semenzato; Arianna Donella-Deana
Journal:  J Clin Invest       Date:  2005-02       Impact factor: 14.808

6.  Chronic lymphocytic leukemia B cells are endowed with the capacity to attract CD4+, CD40L+ T cells by producing CCL22.

Authors:  Paolo Ghia; Giuliana Strola; Luisa Granziero; Massimo Geuna; Giuseppe Guida; Federica Sallusto; Nancy Ruffing; Licia Montagna; Paola Piccoli; Marco Chilosi; Federico Caligaris-Cappio
Journal:  Eur J Immunol       Date:  2002-05       Impact factor: 5.532

7.  An open-label phase 2 trial of entospletinib (GS-9973), a selective spleen tyrosine kinase inhibitor, in chronic lymphocytic leukemia.

Authors:  Jeff Sharman; Michael Hawkins; Kathryn Kolibaba; Michael Boxer; Leonard Klein; Meihua Wu; Jing Hu; Steve Abella; Chris Yasenchak
Journal:  Blood       Date:  2015-02-18       Impact factor: 22.113

8.  Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia.

Authors:  Jonathan W Friedberg; Jeff Sharman; John Sweetenham; Patrick B Johnston; Julie M Vose; Ann Lacasce; Julia Schaefer-Cutillo; Sven De Vos; Rajni Sinha; John P Leonard; Larry D Cripe; Stephanie A Gregory; Michael P Sterba; Ann M Lowe; Ronald Levy; Margaret A Shipp
Journal:  Blood       Date:  2009-11-17       Impact factor: 22.113

9.  Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells.

Authors:  Audun Os; Simone Bürgler; Anna Parente Ribes; Ane Funderud; Dong Wang; Keith M Thompson; Geir E Tjønnfjord; Bjarne Bogen; Ludvig A Munthe
Journal:  Cell Rep       Date:  2013-08-08       Impact factor: 9.423

10.  Fas ligation induces apoptosis of CD40-activated human B lymphocytes.

Authors:  P Garrone; E M Neidhardt; E Garcia; L Galibert; C van Kooten; J Banchereau
Journal:  J Exp Med       Date:  1995-11-01       Impact factor: 14.307

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  5 in total

1.  Phospho Flow Cytometry with Fluorescent Cell Barcoding for Single Cell Signaling Analysis and Biomarker Discovery.

Authors:  Sigrid S Skånland
Journal:  J Vis Exp       Date:  2018-10-04       Impact factor: 1.355

Review 2.  Pediatric precursor B acute lymphoblastic leukemia: are T helper cells the missing link in the infectious etiology theory?

Authors:  Simone Bürgler; David Nadal
Journal:  Mol Cell Pediatr       Date:  2017-05-16

3.  Single cell profiling of phospho-protein levels in chronic lymphocytic leukemia.

Authors:  Ida K Myhrvold; Andrea Cremaschi; Johanne U Hermansen; Geir E Tjønnfjord; Ludvig A Munthe; Kjetil Taskén; Sigrid S Skånland
Journal:  Oncotarget       Date:  2018-01-04

4.  SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia.

Authors:  Cody Paiva; Taylor A Rowland; Bhargava Sreekantham; Claire Godbersen; Scott R Best; Prabhjot Kaur; Marc M Loriaux; Stephen E F Spurgeon; Olga V Danilova; Alexey V Danilov
Journal:  Haematologica       Date:  2017-08-24       Impact factor: 9.941

5.  Cryopreservation of primary B cells minimally influences their signaling responses.

Authors:  Johanne U Hermansen; Geir E Tjønnfjord; Ludvig A Munthe; Kjetil Taskén; Sigrid S Skånland
Journal:  Sci Rep       Date:  2018-12-05       Impact factor: 4.379

  5 in total

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