Literature DB >> 26588433

BODIPY-Coumarin Conjugate as an Endoplasmic Reticulum Membrane Fluidity Sensor and Its Application to ER Stress Models.

Hoyeon Lee1, Zhigang Yang2, Youngjin Wi1, Tae Woo Kim1, Peter Verwilst2, Yun Hak Lee2, Ga-In Han1, Chulhun Kang1, Jong Seung Kim2.   

Abstract

An endoplasmic reticulum (ER) membrane-selective chemosensor composed of BODIPY and coumarin moieties and a long alkyl chain (n-C18) was synthesized. The emission ratio of BODIPY to coumarin depends on the solution viscosity. The probe is localized to the ER membrane and was applied to reveal the reduced ER membrane fluidity under ER stress conditions.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 26588433     DOI: 10.1021/acs.bioconjchem.5b00508

Source DB:  PubMed          Journal:  Bioconjug Chem        ISSN: 1043-1802            Impact factor:   4.774


  2 in total

1.  Localizing Antifungal Drugs to the Correct Organelle Can Markedly Enhance their Efficacy.

Authors:  Raphael I Benhamou; Maayan Bibi; Judith Berman; Micha Fridman
Journal:  Angew Chem Int Ed Engl       Date:  2018-05-02       Impact factor: 15.336

Review 2.  Exploring cells with targeted biosensors.

Authors:  Diana Pendin; Elisa Greotti; Konstantinos Lefkimmiatis; Tullio Pozzan
Journal:  J Gen Physiol       Date:  2016-12-27       Impact factor: 4.086

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.