Literature DB >> 26588038

Aging, cytomegalovirus (CMV) and influenza vaccine responses.

Daniela Frasca1, Bonnie B Blomberg1.   

Abstract

Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have identified immune biomarkers able to predict a protective humoral immune response to the vaccine. In this review, we summarize current knowledge on the effects of aging on influenza vaccine responses and on biomarkers so far identified, and we discuss the relevance of latent cytomegalovirus (CMV) infection on these vaccine responses.

Entities:  

Keywords:  Aging; B cells; CMV; influenza vaccine

Mesh：

Substances：

Year:  2016        PMID： 26588038      PMCID： PMC4964725          DOI： 10.1080/21645515.2015.1105413

Source DB:  PubMed          Journal:  Hum Vaccin Immunother        ISSN： 2164-5515            Impact factor:   3.452


  114 in total

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Review 2.  Characterization of naïve, memory and effector CD8+ T cells: effect of age.

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Journal:  Exp Gerontol       Date:  2004-04       Impact factor: 4.032

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Authors:  Rafael Solana; Graham Pawelec; Raquel Tarazona
Journal:  Immunity       Date:  2006-05       Impact factor: 31.745

4.  Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line.

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Journal:  Genes Dev       Date:  1991-08       Impact factor: 11.361

5.  Influenza vaccination coverage among high-risk groups in 11 European countries.

Authors:  Adrian Loerbroks; Christian Stock; Jos A Bosch; David G Litaker; Christian J Apfelbacher
Journal:  Eur J Public Health       Date:  2011-07-12       Impact factor: 3.367

6.  High TNF-α levels in resting B cells negatively correlate with their response.

Authors:  Daniela Frasca; Alain Diaz; Maria Romero; Ana Marie Landin; Bonnie B Blomberg
Journal:  Exp Gerontol       Date:  2014-01-15       Impact factor: 4.032

Review 7.  The impact of CMV infection on survival in older humans.

Authors:  Graham Pawelec; Janet E McElhaney; Allison E Aiello; Evelyna Derhovanessian
Journal:  Curr Opin Immunol       Date:  2012-04-27       Impact factor: 7.486

8.  Imprint of human cytomegalovirus infection on the NK cell receptor repertoire.

Authors:  Mónica Gumá; Ana Angulo; Carlos Vilches; Natalia Gómez-Lozano; Núria Malats; Miguel López-Botet
Journal:  Blood       Date:  2004-08-10       Impact factor: 22.113

9.  Multifunctional human immunodeficiency virus (HIV) gag-specific CD8+ T-cell responses in rectal mucosa and peripheral blood mononuclear cells during chronic HIV type 1 infection.

Authors:  J William Critchfield; Donna Lemongello; Digna H Walker; Juan C Garcia; David M Asmuth; Richard B Pollard; Barbara L Shacklett
Journal:  J Virol       Date:  2007-03-07       Impact factor: 5.103

10.  CMV latent infection improves CD8+ T response to SEB due to expansion of polyfunctional CD57+ cells in young individuals.

Authors:  Alejandra Pera; Carmen Campos; Alonso Corona; Beatriz Sanchez-Correa; Raquel Tarazona; Anis Larbi; Rafael Solana
Journal:  PLoS One       Date:  2014-02-12       Impact factor: 3.240
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  22 in total

1.  B Cell-Specific Biomarkers for Optimal Antibody Responses to Influenza Vaccination and Molecular Pathways That Reduce B Cell Function with Aging.

Authors:  Daniela Frasca; Bonnie B Blomberg
Journal:  Crit Rev Immunol       Date:  2016       Impact factor: 2.214

Review 2.  Aging of the immune system: Focus on inflammation and vaccination.

Authors:  Marcello Pinti; Victor Appay; Judith Campisi; Daniela Frasca; Tamas Fülöp; Delphine Sauce; Anis Larbi; Birgit Weinberger; Andrea Cossarizza
Journal:  Eur J Immunol       Date:  2016-10       Impact factor: 5.532

3.  Cytomegalovirus serostatus, inflammation, and antibody response to influenza vaccination in older adults: The moderating effect of beta blockade.

Authors:  Rebecca G Reed; Richard N Greenberg; Suzanne C Segerstrom
Journal:  Brain Behav Immun       Date:  2016-10-05       Impact factor: 7.217

4.  Human Cytomegalovirus Seroprevalence Among Blood Donors in the Madinah Region, Saudi Arabia.

Authors:  Waleed Mahallawi; Omar F Khabour; Abdullah Al-Saedi; Ziyad Almuzaini; Nadir Ibrahim
Journal:  Cureus       Date:  2022-02-03

Review 5.  Aging and Options to Halt Declining Immunity to Virus Infections.

Authors:  Miguel Ángel Palacios-Pedrero; Albert D M E Osterhaus; Tanja Becker; Husni Elbahesh; Guus F Rimmelzwaan; Giulietta Saletti
Journal:  Front Immunol       Date:  2021-05-12       Impact factor: 7.561

6.  Cytomegalovirus vaccines under clinical development.

Authors:  Mark R Schleiss
Journal:  J Virus Erad       Date:  2016-10-05

7.  Do human B-lymphocytes avoid aging until 60 years?

Authors:  Andrea Knight; Pavel Nemec; Sona Bretzova; Lucie Valkova; Marketa Kolmanova; Renata Vytopilova; Marek Havelka; Pavla Vsianska; Lucie Rihova; Marta Krejci; Martin Piskacek
Journal:  Oncotarget       Date:  2016-07-12

Review 8.  Potential contribution of gut microbiota and systemic inflammation on HIV vaccine effectiveness and vaccine design.

Authors:  Jean-Pierre Routy; Vikram Mehraj
Journal:  AIDS Res Ther       Date:  2017-09-12       Impact factor: 2.250

Review 9.  Impact of Aging and Cytomegalovirus on Immunological Response to Influenza Vaccination and Infection.

Authors:  Shahzma Merani; Graham Pawelec; George A Kuchel; Janet E McElhaney
Journal:  Front Immunol       Date:  2017-07-17       Impact factor: 7.561

Review 10.  Debunking the Myth of Exercise-Induced Immune Suppression: Redefining the Impact of Exercise on Immunological Health Across the Lifespan.

Authors:  John P Campbell; James E Turner
Journal:  Front Immunol       Date:  2018-04-16       Impact factor: 7.561
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