Literature DB >> 26587333

Melanoma targeting with the loco-regional chemotherapeutic, Melphalan: From cell death to immunotherapeutic efficacy.

Aleksandra Maria Dudek-Perić1, Jakub Gołąb2, Abhishek D Garg1, Patrizia Agostinis1.   

Abstract

All immunoregulatory chemotherapeutics are chiefly applied in a systemic setting for anticancer therapy. However, immune responses following loco-regional application of chemotherapy may differ from those after systemic application. We recently found that Melphalan, a prototypical loco-regionally applied chemotherapeutic agent, exhibits the ability to increase the immunogenicity of dying melanoma cells.

Entities:  

Keywords:  chemotherapy; danger signals; immunogenicity; immunotherapy; melanoma

Year:  2015        PMID： 26587333      PMCID： PMC4635703          DOI： 10.1080/2162402X.2015.1054600

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

Review 1.  The PERKs of damage-associated molecular patterns mediating cancer immunogenicity: From sensor to the plasma membrane and beyond.

Authors:  A R van Vliet; S Martin; A D Garg; P Agostinis
Journal:  Semin Cancer Biol       Date:  2015-04-13       Impact factor: 15.707

2.  Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy.

Authors:  Samuel R Denmeade; Annastasiah M Mhaka; D Marc Rosen; W Nathaniel Brennen; Susan Dalrymple; Ingrid Dach; Claus Olesen; Bora Gurel; Angelo M Demarzo; George Wilding; Michael A Carducci; Craig A Dionne; Jesper V Møller; Poul Nissen; S Brøgger Christensen; John T Isaacs
Journal:  Sci Transl Med       Date:  2012-06-27       Impact factor: 17.956

Review 3.  Cancer immunogenicity, danger signals, and DAMPs: what, when, and how?

Authors:  Abhishek D Garg; Aleksandra M Dudek; Patrizia Agostinis
Journal:  Biofactors       Date:  2013-07-31       Impact factor: 6.113

4.  Improved clinical outcome in indolent B-cell lymphoma patients vaccinated with autologous tumor cells experiencing immunogenic death.

Authors:  Roberta Zappasodi; Serenella M Pupa; Gaia C Ghedini; Italia Bongarzone; Michele Magni; Antonello D Cabras; Mario P Colombo; Carmelo Carlo-Stella; Alessandro M Gianni; Massimo Di Nicola
Journal:  Cancer Res       Date:  2010-09-30       Impact factor: 12.701

5.  Gene expression changes in melanoma metastases in response to high-dose chemotherapy during isolated limb perfusion.

Authors:  Jasper Wouters; Marguerite Stas; Olivier Govaere; Kathleen Van den Eynde; Hugo Vankelecom; Joost J van den Oord
Journal:  Pigment Cell Melanoma Res       Date:  2012-05-03       Impact factor: 4.693

6.  Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin.

Authors:  Aleksandra M Dudek-Perić; Gabriela B Ferreira; Angelika Muchowicz; Jasper Wouters; Nicole Prada; Shaun Martin; Santeri Kiviluoto; Magdalena Winiarska; Louis Boon; Chantal Mathieu; Joost van den Oord; Marguerite Stas; Marie-Lise Gougeon; Jakub Golab; Abhishek D Garg; Patrizia Agostinis
Journal:  Cancer Res       Date:  2015-03-11       Impact factor: 12.701

Review 7.  ER stress, autophagy and immunogenic cell death in photodynamic therapy-induced anti-cancer immune responses.

Authors:  Abhishek D Garg; Patrizia Agostinis
Journal:  Photochem Photobiol Sci       Date:  2014-02-04       Impact factor: 3.982

8.  Immunogenic calreticulin exposure occurs through a phylogenetically conserved stress pathway involving the chemokine CXCL8.

Authors:  A Q Sukkurwala; I Martins; Y Wang; F Schlemmer; C Ruckenstuhl; M Durchschlag; M Michaud; L Senovilla; A Sistigu; Y Ma; E Vacchelli; E Sulpice; X Gidrol; L Zitvogel; F Madeo; L Galluzzi; O Kepp; G Kroemer
Journal:  Cell Death Differ       Date:  2013-06-21       Impact factor: 15.828

Review 9.  Consensus guidelines for the detection of immunogenic cell death.

Authors:  Oliver Kepp; Laura Senovilla; Ilio Vitale; Erika Vacchelli; Sandy Adjemian; Patrizia Agostinis; Lionel Apetoh; Fernando Aranda; Vincenzo Barnaba; Norma Bloy; Laura Bracci; Karine Breckpot; David Brough; Aitziber Buqué; Maria G Castro; Mara Cirone; Maria I Colombo; Isabelle Cremer; Sandra Demaria; Luciana Dini; Aristides G Eliopoulos; Alberto Faggioni; Silvia C Formenti; Jitka Fučíková; Lucia Gabriele; Udo S Gaipl; Jérôme Galon; Abhishek Garg; François Ghiringhelli; Nathalia A Giese; Zong Sheng Guo; Akseli Hemminki; Martin Herrmann; James W Hodge; Stefan Holdenrieder; Jamie Honeychurch; Hong-Min Hu; Xing Huang; Tim M Illidge; Koji Kono; Mladen Korbelik; Dmitri V Krysko; Sherene Loi; Pedro R Lowenstein; Enrico Lugli; Yuting Ma; Frank Madeo; Angelo A Manfredi; Isabelle Martins; Domenico Mavilio; Laurie Menger; Nicolò Merendino; Michael Michaud; Gregoire Mignot; Karen L Mossman; Gabriele Multhoff; Rudolf Oehler; Fabio Palombo; Theocharis Panaretakis; Jonathan Pol; Enrico Proietti; Jean-Ehrland Ricci; Chiara Riganti; Patrizia Rovere-Querini; Anna Rubartelli; Antonella Sistigu; Mark J Smyth; Juergen Sonnemann; Radek Spisek; John Stagg; Abdul Qader Sukkurwala; Eric Tartour; Andrew Thorburn; Stephen H Thorne; Peter Vandenabeele; Francesca Velotti; Samuel T Workenhe; Haining Yang; Wei-Xing Zong; Laurence Zitvogel; Guido Kroemer; Lorenzo Galluzzi
Journal:  Oncoimmunology       Date:  2014-12-13       Impact factor: 8.110

Review 10.  Immature, Semi-Mature, and Fully Mature Dendritic Cells: Toward a DC-Cancer Cells Interface That Augments Anticancer Immunity.

Authors:  Aleksandra M Dudek; Shaun Martin; Abhishek D Garg; Patrizia Agostinis
Journal:  Front Immunol       Date:  2013-12-11       Impact factor: 7.561
  10 in total
  4 in total

Review 1.  Immunostimulatory Effects of Melphalan and Usefulness in Adoptive Cell Therapy with Antitumor CD4+ T Cells.

Authors:  Michal Kuczma; Zhi-Chun Ding; Gang Zhou
Journal:  Crit Rev Immunol       Date:  2016       Impact factor: 2.214

2.  Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in seven patients with peritoneal sarcomatosis from uterine sarcoma.

Authors:  Armando Sardi; Carlos A Muñoz-Zuluaga; Michelle Sittig; Teresa Diaz-Montes
Journal:  Clin Case Rep       Date:  2018-05-02

3.  Discovery of key regulators of dark gland development and hypericin biosynthesis in St. John's Wort (Hypericum perforatum).

Authors:  Paride Rizzo; Lothar Altschmied; Pauline Stark; Twan Rutten; André Gündel; Sarah Scharfenberg; Katrin Franke; Helmut Bäumlein; Ludger Wessjohann; Marcus Koch; Ljudmilla Borisjuk; Timothy F Sharbel
Journal:  Plant Biotechnol J       Date:  2019-05-17       Impact factor: 9.803

Review 4.  The Biochemical and Genetic Basis for the Biosynthesis of Bioactive Compounds in Hypericum Perforatum L., One of the Largest Medicinal Crops in Europe.

Authors:  Paride Rizzo; Lothar Altschmied; Beena M Ravindran; Twan Rutten; John C D'Auria
Journal:  Genes (Basel)       Date:  2020-10-16       Impact factor: 4.096
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.