Literature DB >> 26583936

TCM, brain function and drug space.

Chunping Tang1, Yang Ye2, Yunjiang Feng3, Ronald J Quinn3.   

Abstract

Covering: up to 2015. Traditional Chinese medicine has played a significant role in the mainstream healthcare system in China for thousands of years. Here, we summarize 84 major compounds from 15 selected herbal medicines targeting neurodegenerative diseases. We present a perspective based on the analysis of physicochemical properties of these TCM compounds, and comparison with current drugs and candidates for the treatment of Parkinson's and Alzheimer's disease. The results demonstrate that traditional Chinese medicines contain compounds possessing physicochemical properties that have excellent overlap with developed western medicines.

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Year:  2016        PMID： 26583936     DOI： 10.1039/c5np00049a

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  10 in total

Review 1.  Network Pharmacology in Research of Chinese Medicine Formula: Methodology, Application and Prospective.

Authors:  Ting-Ting Luo; Yuan Lu; Shi-Kai Yan; Xue Xiao; Xiang-Lu Rong; Jiao Guo
Journal:  Chin J Integr Med       Date:  2019-04-02       Impact factor: 1.978

2.  Benzothiazolium Derivative-Capped Silica Nanocomposites for β-Amyloid Imaging In Vivo.

Authors:  Lijun Ma; Shu Yang; Yufan Ma; Yuzhi Chen; Zhenguo Wang; Tony D James; Xuefei Wang; Zhuo Wang
Journal:  Anal Chem       Date:  2021-09-08       Impact factor: 6.986

3.  Network Pharmacology and Molecular Docking-Based Strategy to Investigate the Multitarget Mechanisms of Shenqi Yizhi Granule on Alzheimer's Disease.

Authors:  Linshuang Wang; Xiaoyu Xu; Zikang Wang; Qian Chen; Xiaodie Wei; Jingfan Xue; Zhanjun Zhang; Miao Wang; Yanping Li; Junying Zhang; Dongfeng Wei
Journal:  Evid Based Complement Alternat Med       Date:  2022-04-30       Impact factor: 2.650

4.  Antioxidant Lignans and Neolignans from Acorus tatarinowii.

Authors:  Yuanyuan Lu; Yongbo Xue; Shenjie Chen; Hucheng Zhu; Jinwen Zhang; Xiao-Nian Li; Jianping Wang; JunJun Liu; Changxing Qi; Guang Du; Yonghui Zhang
Journal:  Sci Rep       Date:  2016-03-10       Impact factor: 4.379

5.  Effects of the Tangningtongluo formula as an alternative strategy for diabetics via upregulation of insulin receptor substrate-1.

Authors:  Long Cheng; Junmei Song; Geng Li; Yue Liu; Yuming Wang; Xiangbao Meng; Guibo Sun; Xiaobo Sun
Journal:  Mol Med Rep       Date:  2017-06-01       Impact factor: 2.952

6.  Effects of Combined Bushen Zhichan Recipe and Levodopa in a Rodent Model of Parkinson Disease: Potential Mechanisms.

Authors:  Wenhao Li; Han Gao; Wentao Li
Journal:  Med Sci Monit       Date:  2020-06-19

7.  Low Molecular Weight (poly)Phenol Metabolites Across the Blood-Brain Barrier: The Underexplored Journey.

Authors:  Rafael Carecho; Diogo Carregosa; Cláudia Nunes Dos Santos
Journal:  Brain Plast       Date:  2021-02-09

8.  Potential Targets and Action Mechanism of Gastrodin in the Treatment of Attention-Deficit/Hyperactivity Disorder: Bioinformatics and Network Pharmacology Analysis.

Authors:  Zhe Song; Guangzhi Luo; Chengen Han; Guangyuan Jia; Baoqing Zhang
Journal:  Evid Based Complement Alternat Med       Date:  2022-09-12       Impact factor: 2.650

9.  Ginsenoside Rg3 micelles mitigate doxorubicin-induced cardiotoxicity and enhance its anticancer efficacy.

Authors:  Lan Li; Jingyu Ni; Min Li; Jingrui Chen; Lifeng Han; Yan Zhu; Deling Kong; Jingyuan Mao; Yi Wang; Boli Zhang; Meifeng Zhu; Xiumei Gao; Guanwei Fan
Journal:  Drug Deliv       Date:  2017-11       Impact factor: 6.419

10.  Baicalin Rescues Cognitive Dysfunction, Mitigates Neurodegeneration, and Exerts Anti-Epileptic Effects Through Activating TLR4/MYD88/Caspase-3 Pathway in Rats.

Authors:  Jiali Yang; Zhixia Jia; Zhigang Xiao; Jing Zhao; Ye Lu; Li Chu; Hui Shao; Lin Pei; Shaodan Zhang; Yuan Chen
Journal:  Drug Des Devel Ther       Date:  2021-07-20       Impact factor: 4.162
  10 in total

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