Literature DB >> 2658225

'Nuclear' oncogenes convert extracellular stimuli into changes in the genetic program.

P Herrlich, H Ponta.   

Abstract

Recent discoveries have advanced our understanding of oncogene action: transcription factors are encoded by cellular (nuclear) oncogenes and the activity of transcription factors is modulated in response to extracellular stimuli. Moreover, the nuclear oncoproteins appear to represent the gene-proximal ends of a network of cellular oncoproteins that link extracellular stimuli to the transcriptional machinery and thus to the program of genes a cell will express.

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Year:  1989        PMID： 2658225     DOI： 10.1016/0168-9525(89)90041-3

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  17 in total

Review 1.  Natural biology of polyomavirus middle T antigen.

Authors:  K A Gottlieb; L P Villarreal
Journal:  Microbiol Mol Biol Rev       Date:  2001-06       Impact factor: 11.056

2.  Regulation of collagen I gene expression by ras.

Authors:  J L Slack; M I Parker; V R Robinson; P Bornstein
Journal:  Mol Cell Biol       Date:  1992-10       Impact factor: 4.272

3.  Downregulation of JE and KC genes by glucocorticoids does not prevent the G0----G1 transition in BALB/3T3 cells.

Authors:  L E Rameh; M C Armelin
Journal:  Mol Cell Biol       Date:  1992-10       Impact factor: 4.272

4.  Depletion of c-myc with specific antisense sequences reverses the transformed phenotype in ras oncogene-transformed NIH 3T3 cells.

Authors:  M D Sklar; E Thompson; M J Welsh; M Liebert; J Harney; H B Grossman; M Smith; E V Prochownik
Journal:  Mol Cell Biol       Date:  1991-07       Impact factor: 4.272

5.  A new cAMP response element in the transcribed region of the human c-fos gene.

Authors:  E Härtig; I F Loncarević; M Büscher; P Herrlich; H J Rahmsdorf
Journal:  Nucleic Acids Res       Date:  1991-08-11       Impact factor: 16.971

6.  Stringent integrity requirements for both trans-activation and DNA-binding in a trans-activator, Oct3.

Authors:  M Imagawa; A Miyamoto; M Shirakawa; H Hamada; M Muramatsu
Journal:  Nucleic Acids Res       Date:  1991-08-25       Impact factor: 16.971

7.  Involvement of Ras and AP-1 in Helicobacter pylori-induced expression of COX-2 and iNOS in gastric epithelial AGS cells.

Authors:  Soon Ok Cho; Joo Weon Lim; Kyung Hwan Kim; Hyeyoung Kim
Journal:  Dig Dis Sci       Date:  2009-06-03       Impact factor: 3.199

8.  Analysis of signaling protein kinases in human colon or colorectal carcinomas.

Authors:  L L Licato; D A Brenner
Journal:  Dig Dis Sci       Date:  1998-07       Impact factor: 3.199

9.  An ATF/CREB binding motif is required for aberrant constitutive expression of the MHC class II DR alpha promoter and activation by SV40 T-antigen.

Authors:  P M Cox; C R Goding
Journal:  Nucleic Acids Res       Date:  1992-09-25       Impact factor: 16.971

10.  Molecular characterization of the in vivo alkylating agent resistant murine EMT-6 mammary carcinoma tumors.

Authors:  D Chatterjee; C J Liu; D Northey; B A Teicher
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333
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